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                                                             Chapter 7: Disorders of conciousness and memory 309


                  Table 7.7 Types of seizures
                  Type of seizure                  Description
                  Partial seizures
                    Simple partial (consciousness maintained)  Motor: usually twitching or jerking of one side of the face, or one limb.
                                                   Sensory, e.g. auditory or somatosensory.
                                                   Autonomic: pallor, sweating, etc.
                                                   There may be a Jacksonian March, with the epilepsy progressively involving more
                                                    of a limb, e.g. hand, then elbow, then shoulder.
                    Complex partial (impaired conciousness)  May begin as a simple partial then become complex, or be complex from the
                                                    start.
                                                   Often with disturbance of higher cerebral function, e.g. sense of fear.
                                                    Semi-purposeful movements may occur.
                                                   The patient has little or no recall of the episode.
                  Secondary generalised            Partial seizures (simple or complex) can progress to secondary generalised
                                                    seizures.
                  Generalised seizures
                    Nonconvulsive (absence)        Impaired conciousness but without falling, although there may be involuntary
                                                    movements. Usually last less then 20 s. EEG shows characteristic 3 per second
                                                    spike and wave discharges
                    Convulsive (usually followed by
                     post-ictal confusion)
                     Myoclonic                     Sudden shock-like jerks affecting one part or the whole body
                     Clonic                        Generalised jerking
                     Tonic                         Rigidity, increased tone, respiration ceases
                     Tonic–clonic                  Initial rigid tonic stage during which respiration ceases, then generalised jerking
                                                   Micturition, salivation and tongue-biting may occur. If this lasts >30 min, it is
                                                    called status epilepticus.
                     Atonic (drop attacks)         Loss of muscle tone causing patient to fall to ground



                    The main terms used to describe seizures are:  gitis, stroke etc which may need urgent treatment. It is
                  Partial (focal, localised seizure)            also important to decide if the patient is likely to have
                      A partial seizure may be simple (no loss of con-  further seizures.

                      sciousness) or complex (impaired consciousness).     Iftheseizurelasts<10minuteswithfullrecovery,with
                  Generalised (diffuse, whole brain affected)    no neurological or systemic disorder the patient can
                      Ageneralised seizure may be convulsive (jerking,  usually be discharged home after a period of observa-

                      with motor involvement) or non-convulsive (ab-  tion. They should be accompanied and be advised not
                      sence, motor tone unaffected).             to drive (see below).
                                                                 If unwell, pyrexial, persisting neurology or prolonged

                  Investigations                                 confusion post-seizure – urgent investigation with
                  The urgency of the tests depends on the clinical findings.  imaging, blood test, possibly lumbar puncture is re-
                    Blood tests – FBC, U&Es, glucose, calcium, magne-  quired.

                    sium, LFTs and thyroid function tests.         Prolonged seizures or recurring seizures require inpa-
                    ECG.                                         tient admission for monitoring and initiation of treat-

                    EEG may be normal even in genuine epilepsy.  ment to control seizures.

                    MRI(orCTwhereMRIisnotavailable)isincreasingly

                    used in all patients to look for an underlying lesion.
                                                                Status epilepticus
                  Management                                    This is defined as a prolonged single attack or continuing
                  With a first seizure, it is important to exclude any under-  attacks of epilepsy without intervals of consciousness.
                  lying cause such as a biochemical disturbance, menin-  The duration at which status is diagnosed is variable,
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