Page 81 - Medicine and Surgery
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                                                                 Chapter 2: Hypertension and vascular diseases 77


                    paraesthesia and paralysis, which is a surgical emer-  popliteal or tibial artery as the stenosis or occlu-
                    gency (see page 80).                             sion is usually long.
                                                                 4 Amputation:vasculardiseasecausesmorethan90%
                                                                   of all amputations; however, most vascular disease
                  Investigations
                                                                   does not result in this. The level of amputation is
                    X-ray may show calcification of the vessels in the leg.

                                                                   dependent on blood supply, state of joints, general
                    Doppler ultrasound to measure ankle systolic blood

                                                                   health and age. Conservation of the knee joint is im-
                    pressure and assess blood flow.
                                                                   portant (possible in 50%) for prosthesis and walk-
                    Arteriography or digital subtraction angiography al-

                                                                   ing.Normallythestumpisclosedbyprimarysuture.
                    lows visualisation of the arterial tree.
                                                                Prognosis
                  Management
                                                                Five-year patency rates with femoro-distal bypass vary
                    Risk factors should be modified where possible, stop-

                                                                between 30 and 50%, aortoiliac reconstruction has a pa-
                    ping smoking in particular may prevent further dete-
                                                                tency rate of 80%. The most common cause of death
                    riorationandimprovessymptomsinmanycases.Care
                                                                peri-operatively and during long-term follow-up is is-
                    should be taken to avoid trauma. Exercise should be
                                                                chaemic heart disease.
                    encouraged as it improves collateral supply.
                    Low-dose aspirin should be used to reduce risk of

                    thromboembolism.                            Aneurysms
                    In most patients clinical symptoms are static or fluc-

                    tuate, so conservative care is sufficient. There are four  Definition
                    options for persistently severe symptoms. Arterioscle-  An aneurysm is defined as an abnormal focal dilation of
                    rosis in older patients is difficult to treat surgically, as  an artery (see Table 2.12).
                    the vessels are small.
                    1 Sympathectomy reduces vasospasm. It is useful to
                                                                Pathophysiology
                      relieve rest pain in small vessel disease. It can be
                                                                   An arterial aneurysm may be true or false. A true
                      done percutaneously with an injection of phenol.
                                                                 aneurysm is enclosed by all three layers of the arte-
                    2 Percutaneous angioplasty is most useful for short
                                                                 rial wall. A true aneurysm may be further subdivided
                      stenoses or occlusions in medium-sized arteries
                                                                 into saccular in which there is a focal out-pouching
                      suchastheiliac,femoralandrenalarteries;however,
                                                                 or fusiform where there is dilation of the whole cir-
                      as patients often present late the disease may be too
                                                                 cumference of the vessel. A false (pseudo) aneurysm
                      widespread. A guide wire is inserted and then a bal-
                                                                 occurs following penetrating trauma when there is a
                      loon fed over the wire and inflated within the lesion.
                                                                 pulsatile haematoma, which is in contact with the ar-
                      Stentsareoftenusedtoimprovepatency.Complica-
                                                                 terial lumen.
                      tions include restenosis, dissection or thrombosis.
                                                                   Aneurysms tend to slowly enlarge, causing local pres-
                    3 Arterial reconstruction is preferably reserved for
                                                                 sure problems. They may dissect and cut off blood
                      critical ischaemia or severely limiting intermittent
                                                                 supply to tissue or rupture with resulting haemor-
                      claudication, because failed grafting worsens symp-
                                                                 rhage.
                      toms and repeat surgery is very difficult. In addi-
                                                                   Altered flow patterns predispose to thrombus forma-
                      tion, most patients have other conditions such as
                                                                 tion, which may embolise to distal arteries or cause
                      ischaemic heart disease, diabetes and cerebrovascu-
                                                                 occlusion at the site of the aneurysm.
                      lar disease, which increases peri- and postoperative
                      morbidity and mortality. Procedures include
                        femoro-popliteal grafts using saphenous vein, or  Investigations

                        polytetrafluorethylene (PTFE) and        CT and ultrasound scanning can demonstrate the posi-
                        more distal disease is best treated with a bypass  tion and type of aneurysm. Arteriography or 3-D recon-

                        graft from the common femoral artery to the  struction using MRI is used to outline the anatomy.
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