Page 26 - AAOMP Meeting 2019

POSTER ABSTRACTS - TUESDAY, JUNE 11, 2019

#3 BENIGN FIBROUS HISTIOCYTOMA OF THE JAWBONES. REPORT OF 5 CASES WITH
REVIEW OF THE LITERATURE
Dr. Robert Feliciano (New York Presbyterian Queens), Dr. Renee Reich (New York Presbyterian
Queens), Dr. Chelsea Wilson (New), Dr. Paul Freedman (New York Presbyterian Queens)
Introduction: Benign fibrous histiocytomas (BFH) are mesenchymal tumors composed of a mixture of
fibroblasts and histiocytes arranged in a storiform pattern. This benign neoplasm most often occurs in the
skin of the lower extremities and rarely affects bone. BFH of bone occur most frequently in the femur,
pelvis and tibia comprising approximately 1% of all benign bone tumors. Jawbone involvement is
extremely rare with only 13 cases having been reported in the literature as of 2016. In 2017, we presented
two new cases at the AAOMP annual meeting. Here we present an additional 3 cases.
Materials and Methods: The files of our biopsy service and consultative service were searched from 1984 to
2019 for cases with the diagnosis of benign fibrous histiocytoma of the jawbone. Three additional cases of
BFH of the jawbones were identified. These three cases and the two cases presented in 2017 were
analyzed for their histologic, immunohistochemical and demographic features.
Results: Of our five cases of BFH of the jawbone, four involved the mandible and one occurred in the
maxilla. There was no sex predilection. The age range was 17 to 48 years. The tumors presented as expansile
painless radiolucent lesions. Histologically, the tumors consisted of spindle shaped cells arranged in a
storiform pattern. Secondary elements were present consisting of inflammatory cells and foamy histiocytes.
Immunohistochemical studies revealed CD10, Factor XIIIa and CD68 positivity for three of the five cases.
Conclusions: BFH of the jawbones are rare tumors. The addition of our five cases brings the total to 18 cases
in the literature. The lesions cause painless expansion and appear histologically as spindle cells arranged in a
storiform patter. Secondary elements may be evident. Staining for CD10, CD 68 and Factor XIIIa may be
useful is distinguishing these tumors from other spindle cell lesions.

#4 A CASE REPORT OF LINGUAL BRONCHOGENIC CYST
Dr. Zahra Aldawood (Department of Oral Medicine, Infection, and Immunity, Harvard School of
Dental Medicine), Dr. Sook-Bin Woo (Department of Oral Medicine, Infection and Immunity, Harvard
School of Dental Medicine)
Bronchogenic cysts are foregut-derived developmental anomalies found along the developmental pathway
of the foregut. The putative theory of pathogenesis is abnormal budding or branching of epithelial cells
during the development of tracheobronchial tree. The most common sites are mediastinum and lung (75%
and 25 % of case respectively) while the head and neck are affected in less than 1% of cases with only rare
cases reported in the oral cavity. It is usually asymptomatic but if it becomes large, it may cause feeding and
breathing difficulties. This is a report of a case of a bronchogenic cyst arising in a 6-year-old male. The
lesion presented as deep mucosal mass in the midline of ventral tongue, measuring 1.1 × 0.7 × 0.7 cm.
Microscopically, the cyst was lined by pseudostratified columnar epithelium exhibiting many ciliated and
mucous cells. A focus of cartilage and discontinuous bundles of smooth muscle (smooth muscle actin
positive) were present adjacent to the lining. Where there was cyst rupture, there was granulation tissue
associated with many foamy macrophages and acute and chronic inflammation. Three other cases, two in the
tongue and one in the lower lip vestibule with cutaneous extension, all in the midline, have been reported in
a 1 day-old, 4 year-old and 3 year-old; all were males. There was no recurrence after excision and this is in
keeping with the behavior in previous reports. Other developmental cysts including foregut cysts may be
focally lined with respiratory epithelium but the presence of cartilage is the sine qua non for the diagnosis
of a bronchogenic cyst.