Page 24 - Spring 18

Cushing's disease
María González Gómez, Argentina
Introduction
Cushing syndrome hyperadrenocorticism or endocrine disease is a common clinical presentation being more common in geriatric dogs. It appears as a result of persistently elevated levels of plasma cortisol. Adenoma and hyperplasia of the pituitary gland are cited as the most frequent causes of disease, accounting for 80-90% of cases of spontaneous hyperadrenocorticism. Excessive ACTH secretion causes a bilateral adrenal hyperplasia of both cortices with the consequent producing and excessive amounts of cortisol. 10 to 20 % of the remaining cases are due to adrenal neoplasms.
The control mechanism (feedback) of the Hypothalamic – Pituitary - Adrenal axis is the following: the hypothalamus synthesises CRH, which stimulates the anterior pituitary gland to synthesise ACTH. This hormone reaches the adrenal cortex stimulating the synthesis of cortisol. To this control mechanism can be added some suprahypothalamic factors that inhibit the formation of CRH (endorphins, somatostatin and progesterone) and others that stimulate (ADH, catecholamines and emotional stressors). Meanwhile cortisol acts by a mechanism of a long feedback on the anterior pituitary gland and hypothalamus, causing the amount of ACTH and CRH synthesised in their respective axes to decrease. In addition, it also acts on the adrenal cortex itself, reducing Cortisol synthesis. ACTH acts through a short Feedback mechanism on the hypothalamus, decreasing the amount of CRH it produces. Finally, the hypothalamus acts by a mechanism of ultra short feedback on the hypothalamus itself, thus reducing the synthesis of CRH.
In homeopathy the following Hippocratic statement is reinforced: "There are no diseases but sick" and a deep
knowledge of the patient is proposed. However, such statements should not lead to the veterinarian to neglect the deep study of diseases. First we are doctors and then we form as homeopaths. In Cushing's syndrome it is helpful to arrive at the correct diagnosis that allows us to determine if its origin is pituitary or adrenal, especially when we cannot find the constitutional remedy and we should use timely organotherapeutics.
Today the presentation of this manifestation of disease in the canine species has greatly increased; this should lead us to ask why? From a nonlinear holistic approach, the answer is multifactorial, being interesting to note some situations that are repeated in daily clinical practice, making us think of predisposing factors. Since the canine and feline species became part of the human family system, veterinarians daily observe a relationship between family conflict and disease in our patients. Within this close coexistence, they are an integral part of our electromagnetic field. According to the dictionary, a field is a "region or area where there is a certain effect." Probably you've heard of magnetic fields such as those formed around the microwave oven. Or maybe have perceived the fields of sacred places such as cities with ancient pyramids, Holy Land, etc. We all have personal fields. Surely you have noticed how some people produce a warm and inviting feel, and others, however, seem to emanate a kind of energy that says "Do not come near me!"
More than 18 years ago, I have used the term "external organ of somatisation" to refer to this "energy infection" that occurs from human to animal, by simply entering its electromagnetic field and soak emotions and conflicts lived by her guardian. Dr. Ryke Geerd Hamer, father of the new Germanic medicine, enunciated during the 80’s and 90’s, the five biological laws that meant a breakthrough in the
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