Page 7 - NowAware_Press Kit

REaD Edge
Us vs. Them
Why
REaD consistently indicates the presence of COVID-19 specific enzymes in infected cells before the viral load is sufficient for PCR detection whether or not a patient ever becomes symptomatic.
Because these enzymes are conserved within the MERS and SARS classes, this test can detect future generations of COVID-19 that PCR methodology may not.
REaD relies on a patented technology of testing for the existence of the virus that has low rate of false negatives.
PCR tests take a molecular biology approach that has limitations which cause a high rate of false negative results.
REaD can detect the COVID-19 enzyme days before there is enough detectable virus by RT-PCR, due to the ratio of enzymes in the host cells that are infected with the COVID -19 virus within our tongue sample approach.
RT-PCR is designed to identify only a known sequence in the virus, and there are a host of factors that can drive RT-PCR tests to have larger number of false negatives.
Comparison
Time to Complete
Customer Comfort
Accuracy
Throughput/lab/week
PCR
3+ hours
False sense of confidence, repeat testing difficult
Questionable—dead virus RNA fragments lingering in the body will produce false positives with PCR tests
<105
REaDTM test
Edge
Reliability
Low (high rate of false negatives)
Consistency
Inconsistent results across different test laboratories
Throughput/lab/day <15
Throughput/lab/month <450
Minutes High
High confidence, repeatability Repeatable process
High—once the virus is dead, no PLpro or 3CL pro will be produced by the host cells
4,608,000 32,256,000 138,240,000
REaD
REaD
REaD
REaD
REaD
REaD
REaD
REaD
Since the validation of our test, we are finding several instances where RT-PCR confirmed negative samples have shown strong fluorescence signal
with REaD. Given that all REaD negative samples having resulted in low signals, we believe REaD is detecting rapid enzyme activity that can only come from infected cells in the tongue sample.
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