Page 47 - CBAC Newsletter 2017

Castellano BM, Thelen AM, Moldavski O, Feltes M, van der Welle RE, Mydock-McGrane L, Jiang X,
van Eijkeren RJ, Davis OB, Louie SM, Perera RM, Covey DF, Nomura DK, Ory DS, Zoncu R. Lysosomal
cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex. Science.
2017 Mar 24;355(6331):1306-1311. PMID: 28336668
Dai S, Dulcey AE, Hu X, Wassif CA, Porter FD, Austin CP, Ory DS, Marugan J, Zheng W. Methyl-β-cyclodextrin restores
impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK. Autophagy. 2017 Jun
14:0. [Epub ahead of print]. PMID: 28613987, PMCID: PMC5584846

Maria S. Remedi, Ph.D.

Remedi MS, Emfinger C. Pancreatic β-cell identity in diabetes. Diabetes Obes Metab. 2016 Sep;18 Suppl 1:110-6.
Review. PMID: 27615139, PMCID: PMC5021188
Lee J, Harris AN, Holley CL, Mahadevan J, Pyles KD, Lavagnino Z, Scherrer DE, Fujiwara H, Sidhu R, Zhang J,
Huang SC, Piston DW, Remedi MS, Urano F, Ory DS, Schaffer JE. Rpl13a small nucleolar RNAs regulate
systemic glucose metabolism. J Clin Invest. 2016 Dec 1;126(12):4616-4625. Epub 2016 Nov 7.
PMID: 27820699, PMCID: PMC5127695
Remedi MS, Friedman JB, Nichols CG. Diabetes induced by gain-of-function mutations in the Kir6.1 subunit of the
KATP channel. J Gen Physiol. 2017 Jan;149(1):75-84. Epub 2016 Dec 12. PMID: 27956473,
PMCID: PMC5217086
Remedi MS, Thomas M, Nichols CG, Marshall BA. Sulfonylurea challenge test in subjects diagnosed with type 1
diabetes mellitus. Pediatr Diabetes. 2017 Jan 23. [Epub ahead of print]. PMID: 28111849
Asghar ZA, Cusumano A, Yan Z, Remedi MS, Moley KH. Reduced islet function contributes to impaired glucose
homeostasis in fructose-fed mice. Am J Physiol Endocrinol Metab. 2017 Feb 1;312(2):E109-E116.
Epub 2016 Dec 27. PMID: 28028036, PMCID: PMC5336566
Emfinger CH, Welscher A, Yan Z, Wang Y, Conway H, Moss JB, Moss LG, Remedi MS, Nichols CG. Expression and
function of ATP-dependent potassium channels in zebrafish islet β-cells. R Soc Open Sci.
2017 Feb 8;4(2):160808. eCollection 2017 Feb. PMID: 28386438, PMCID: PMC5367309
Remedi MS. Should I Stay or Should I Go: A Clash of α-Cell Identity. Cell Metab. 2017 Mar 7;25(3):488-490.
PMID: 28273469

stacey rentschler, M.D., Ph.D.

Kang C, Qiao Y, Li G, Baechle K, Camelliti P, Rentschler S, Efimov IR. Human Organotypic Cultured Cardiac Slices:
New Platform For High Throughput Preclinical Human Trials. Sci Rep. 2016 Jun 30;6:28798.
PMID: 27356882, PMCID: PMC4928074
Díaz-Trelles R, Scimia MC, Bushway P, Tran D, Monosov A, Monosov E, Peterson K, Rentschler S, Cabrales P,
Ruiz-Lozano P, Mercola M. Notch-independent RBPJ controls angiogenesis in the adult heart. Nat Commun.
2016 Jun 30;7:12088. PMID: 27357444, PMCID: PMC4931341
Khandekar A, Springer S, Wang W, Hicks S, Weinheimer C, Diaz-Trelles R, Nerbonne JM, Rentschler S.
Notch-Mediated Epigenetic Regulation of Voltage-Gated Potassium Currents. Circ Res. 2016 Dec
9;119(12):1324-1338. Epub 2016 Oct 3. PMID: 27697822, PMCID: PMC5148677
Weber LK, Palermo A, Kügler J, Armant O, Isse A, Rentschler S, Jaenisch T, Hubbuch J, Dübel S, Nesterov-Mueller A,
Breitling F, Loeffler FF. Single amino acid fingerprinting of the human antibody repertoire with high density
peptide arrays. J Immunol Methods. 2017 Apr;443:45-54. Epub 2017 Feb 3. PMID: 28167275

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