Page 11 - CBAC Newsletter 2014
P. 11
Fig. 1. Genetic manipulations in mice can reprogram the development of the
conduction system. (A) There are more Purkinje cells in the left bundle branch of
wild-type (WT) than Nkx2-5+/- (HET) mice, as depicted by a Cx40-GFP reporter. (B)
The number of Purkinje cells in the right bundle branch of mice in which Notch signal-
ing is activated (+) is greater than in the control (-).
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