Page 28 - CBAC Newsletter 2014

News & ANNouNcemeNts
coNtiNued

novemBer 2013 (Cont.’d)

Poster Presentations by CBAC members included:

• “Pro-Arrhythmogenic Effects of the KCNQ1-V141M Mutation in Short QT Syndrome and Its Potential
Therapeutic Targets - Insights From Modeling” by Hsiang-Chun Lee and Jianmin Cui
• “Diastolic Function in Normal Sinus Rhythm Vs. Chronic Atrial Fibrillation: Quantitative Comparison
by Fractionation of E-wave Deceleration Time into Stiffness and Relaxation Components”
by Sándor Kovács
• “Model-based Reexpression of Vortex Formation Time Differentiates Between Pseudonormal vs.
Normal Left Ventricular Echocardiographic Filling Patterns” by graduate student Erina Ghosh and
Sándor Kovács
• “Transgenic Expression of a Kir6.1 Gain-of-Function Mutation in the Mouse Heart Reults in Av Nodal
Conduction Abnormalities” by Research Instructor Haixia Zhang and Colin Nichols
• “Voltage-Clamp Fluorometry Reveals a Unique Cardiac Phenotype for the hNaV1.5 DIII and DIV
Voltage Sensors” by Jonathan Silva
• “Flourescence Tracking of Domain IV Voltage Sensor Motion Shows a Progressively Varying Molecular
Phenotype in Long QT Syndrome Type 3 Mutants” by researcher Angela Schubert and
Jonathan Silva
• “Distinct Mechanism of Lidocaine Interation with the DIII Voltage Sensor of the Cardiac Sodium
Channel” by Zoltan Varga and Jonathan Silva
• “Thrombin-Inhibiting Nanoparticles Prevent Growth of Fibrin Clots by Inhibiting and Adhering to
Clot-Bound Thrombin by graduate student Jacob W. Myerson and Samuel Wickline
• “Maturational Changes in Myocardial Mechanics During the First Month of Life in Healthy Full term
Neonates” by Instructor Philip Levy and Gautam Singh

deCemBer 2013

Yoram Rudy, gave the keynote address entitled:“Mechanisms of Human Cardiac Arrhythmias: Noninvasive Studies
with Electrocardiographic Imaging (ECGI)” at the University of Milano Department of Biotechnology and Biosciences,
Department Day Celebration on December 5, 2013.
January 2014

Patrick Jay received the Established Investigator Award
by the American Heart Association (AHA), a $400,000
five-year award, for the project titled, “Maternal Age: A
Modifiable Risk Factor for Congenital Heart Disease”

FeBruary 2014

Igor Efimov and an international team of biomedical engineers and materials scientists have created a 3-D elastic
membrane made of a soft, flexible, silicon material that is precisely shaped to match the heart’s epicardium, or the
outer layer of the wall of the heart. Link: http://engineering.wustl.edu/newsstory.aspx?news=7560

Philip Bayly received the Richard Skalak Award for outstanding paper in the Journal of Biomechanical Engineering.

23 | CBAC Center Heartbeat