Page 45 - CBAC Newsletter 2014

Fan M, Sidhu R, Fujiwara H, Tortelli B, Zhang J, Davidson C, Walkley SU, Bagel JH, Vite C, Yanjanin NM, Porter FD,
Schaffer JE, Ory DS. Identification of Niemann-Pick C1 disease biomarkers through sphingolipid profiling.
J Lipid Res. 2013 Oct;54(10):2800-14. PMCID: 3770093
Hawkins-Salsbury JA, Parameswar AR, Jiang X, Schlesinger PH, Bongarzone E, Ory DS, Demchenko AV, Sands MS.
Psychosine, the cytotoxic sphingolipid that accumulates in globoid cell leukodystrophy, alters membrane
architecture. J Lipid Res. 2013 Dec;54(12):3303-11. PMCID: 3826678
Olsen BN, Bielska AA, Lee T, Daily MD, Covey DF, Schlesinger PH, Baker NA, Ory DS. The structural basis of
cholesterol accessibility in membranes. Biophys J. 2013 Oct 15;105(8):1838-47. PMCID: 3797575
Brandis KA, Gale S, Jinn S, Langmade SJ, Dudley-Rucker N, Jiang H, Sidhu R, Ren A, Goldberg A, Schaffer JE, Ory DS.
Box C/D small nucleolar RNA (snoRNA) U60 regulates intracellular cholesterol trafficking. J Biol Chem. 2013
Dec 13;288(50):35703-13. PMCID: 3861622
Speak AO, Te Vruchte D, Davis LC, Morgan AJ, Smith DA, Yanjanin NM, Simmons L, Hartung R, Runz H, Mengel E,
Beck M, Imrie J, Jacklin E, Wraith JE, Hendriksz C, Lachmann R, Cognet C, Sidhu R, Fujiwara H, Ory DS,
Galione A, Porter FD, Vivier E, Platt FM. Altered distribution and function of natural killer cells in murine and
human Niemann-Pick disease type C1. Blood. 2014 Jan 2;123(1):51-60. PMCID: 3879905
te Vruchte D, Speak AO, Wallom KL, Al Eisa N, Smith DA, Hendriksz CJ, Simmons L, Lachmann RH, Cousins A,
Hartung R, Mengel E, Runz H, Beck M, Amraoui Y, Imrie J, Jacklin E, Riddick K, Yanjanin NM, Wassif CA, Rolfs
A, Rimmele F, Wright N, Taylor C, Ramaswami U, Cox TM, Hastings C, Jiang X, Sidhu R, Ory DS, Arias B,
Jeyakumar M, Sillence DJ, Wraith JE, Porter FD, Cortina-Borja M, Platt FM. Relative acidic compartment
volume as a lysosomal storage disorder-associated biomarker. J Clin Invest. 2014 Mar 3;124(3):1320-8.
PMCID: 3934186
Peyrot SM, Nachtergaele S, Luchetti G, Mydock-McGrane LK, Fujiwara H, Scherrer D, Jallouk A, Schlesinger PH, Ory
DS, Covey DF, Rohatgi R. Tracking the subcellular fate of 20(s)-hydroxycholesterol with click chemistry reveals
a transport pathway to the Golgi. J Biol Chem. 2014 Apr 18;289(16):11095-110. PMCID: 4036249
Bielska AA, Olsen BN, Gale SE, Mydock-McGrane L, Krishnan K, Baker NA, Schlesinger PH, Covey DF, Ory DS.
Side-Chain Oxysterols Modulate Cholesterol Accessibility through Membrane Remodeling. Biochemistry.
2014 May 13;53(18):3042-51. PMCID: 4020583
Daily MD, Olsen BN, Schlesinger PH, Ory DS, Baker NA. Improved Coarse-Grained Modeling of Cholesterol-Containing
Lipid Bilayers. J Chem Theory Comput. 2014 May 13;10(5):2137-2150.

STACEY L. RENTSCHLER, M.D., Ph.D.

Addis RC, Ifkovits JL, Pinto F, Kellam LK, Esteso P, Rentschler S, Christoforou N, Epstein JA, and Gearhart JD.
Optimization of Direct Fibroblast Reprogramming to Cardiomyocytes using Calcium Activity as a Functional
Measure of Success. J Mol Cell Cardiol, 2013; 60C:97-106 PMCID: 3679282
Smith AW, Hoyne JD, Nguyen PK, McCreedy DA, Aly H, Efimov IR, Rentschler S, Elbert DL. Direct reprogramming of
mouse fibroblasts to cardiomyocyte-like cells using Yamanaka factors on engineered poly(ethylene glycol)
(PEG) hydrogels. Biomaterials, 2013; 34(28):6559-71 PMCID: 3698604
Dawson M, Pajcini KV, D-altri T, Tu L, Jain R, Xu L, Chen M, Rentschler S, Shestova O, Werthheim GB, Kluke M, Aster
JC, Gimotty P, Epstein JA, Speck N, Bigas A, Pear WS. Notch1 transcriptional activation domain is required for
development and reveals a novel role for Notch1 signaling in fetal HSCs. Genes and Development,
2014;28(6):576-93

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