Page 56 - CBAC Newsletter 2016

Publications

July 2015 - July 2016

colin g. nichols, Ph.D.

Henn MC, Janjua MB, Zhang H, Kanter EM, Makepeace CM, Schuessler RB, Nichols CG, Lawton JS. Diazoxide
cardioprotection is independent of adenosine triphosphate-sensitive potassium channel Kir6.1 subunit in
response to stress. J Am Coll Surg. 2015 Aug;221(2):319-25. Epub 2015 Feb 21. PMID: 25872691,
PMCID: PMC4515177
Zubcevic L, Wang S, Bavro VN, Lee SJ, Nichols CG, Tucker SJ. (2015) Modular design of the selectivity filter pore loop
in a novel family of prokaryotic 'inward rectifier' (NirBac) channels. Sci Rep. 2015 Oct 16;5:15305.
PMID: 26470642, PMCID: PMC4607889
Li DC, Nichols CG, Sala-Rabanal M. Role of a Hydrophobic Pocket in Polyamine Interactions with the Polyspecific
Organic Cation Transporter OCT3. J Biol Chem. 2015 Nov 13;290(46):27633-43. Epub 2015 Sep 24.
PMID: 26405039, PMCID: PMC4646014
Henn MC, Janjua MB, Kanter EM, Makepeace CM, Schuessler RB, Nichols CG, Lawton JS. Adenosine
Triphosphate-Sensitive Potassium Channel Kir Subunits Implicated in Cardioprotection by Diazoxide.
J Am Heart Assoc. 2015 Aug 24;4(8):e002016. PMID: 26304939, PMCID: PMC4599460
Baier LJ, Muller YL, Remedi MS, Traurig M, Piaggi P, Wiessner G, Huang K, Stacy A, Kobes S, Krakoff J, Bennett PH,
Nelson RG, Knowler WC, Hanson RL, Nichols CG, Bogardus C. ABCC8 R1420H Loss-of-Function Variant in a
Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of
Type 2 Diabetes. Diabetes. 2015 Dec;64(12):4322-32. Epub 2015 Aug 5. PMID: 26246406,
PMCID: PMC4657583
Nelson PT, Jicha GA, Wang WX, Ighodaro E, Artiushin S, Nichols CG, Fardo DW. ABCC9/SUR2 in the brain: Implications
for hippocampal sclerosis of aging and a potential therapeutic target. Ageing Res Rev.
2015 Nov;24(Pt B):111-25. Epub 2015 Jul 28. Review. PMID: 26226329, PMCID: PMC4661124
Levin MD, Zhang H, Uchida K, Grange DK, Singh GK, Nichols CG. Electrophysiologic consequences of KATP gain of
function in the heart: Conduction abnormalities in Cantu syndrome. Heart Rhythm.
2015 Nov;12(11):2316-24. Epub 2015 Jun 30. PMID: 26142302, PMCID: PMC4624040
Cooper PE, Sala-Rabanal M, Lee SJ, Nichols CG. Differential mechanisms of Cantú syndrome-associated gain of
function mutations in the ABCC9 (SUR2) subunit of the KATP channel. J Gen Physiol.
2015 Dec;146(6):527-40. PMID: 26621776, PMCID: PMC4664827
Wang S, Vafabakhsh R, Borschel WF, Ha T, Nichols CG. Structural dynamics of potassium-channel gating revealed by
single-molecule FRET. Nat Struct Mol Biol. 2016 Jan;23(1):31-6. Epub 2015 Dec 7.
PMID: 26641713, PMCID: PMC4833211
Méndez-González MP, Kucheryavykh YV, Zayas-Santiago A, Vélez-Carrasco W, Maldonado-Martínez G, Cubano LA,
Nichols CG, Skatchkov SN, Eaton MJ. Novel KCNJ10 Gene Variations Compromise Function of Inwardly
Rectifying Potassium Channel 4.1. J Biol Chem. 2016 Apr 1;291(14):7716-26.
Epub 2016 Feb 11.PMID: 26867573, PMCID: PMC4817196
Levin MD, Singh GK, Zhang HX, Uchida K, Kozel BA, Stein PK, Kovacs A, Westenbroek RE, Catterall WA, Grange DK,
Nichols CG. KATP channel gain-of-function leads to increased myocardial L-type Ca2+ current and
contractility in Cantu syndrome. Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):6773-8. Epub 2016 May 31.
PMID: 27247394, PMCID: PMC4914204
Leon Guerrero CR, Pathak S, Grange DK, Singh GK, Nichols CG, Lee JM, Vo KD. Neurologic and neuroimaging
manifestations of Cantú syndrome: A case series. Neurology. 2016 Jun 17. pii: 10.1212/

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