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A12   HEALTH
               Thursday 24 december 2020
            Studies find having COVID-19 may protect against reinfection



            AP Chief Medical Writer                                                                                             two  private  labs  in  the
            Two  new  studies  give  en-                                                                                        United States. Only 0.3% of
            couraging  evidence  that                                                                                           those who initially had anti-
            having COVID-19 may offer                                                                                           bodies later tested positive
            some  protection  against                                                                                           for  the  coronavirus,  com-
            future infections. Research-                                                                                        pared with 3% of those who
            ers found that people who                                                                                           lacked such antibodies.
            made  antibodies  to  the                                                                                           "It's  very  gratifying"  to  see
            coronavirus were much less                                                                                          that the Oxford researchers
            likely to test positive again                                                                                       saw  the  same  risk  reduc-
            for  up  to  six  months  and                                                                                       tion — 10 times less likely to
            maybe longer.                                                                                                       have a second infection if
            The  results  bode  well  for                                                                                       antibodies  were  present,
            vaccines,  which  provoke                                                                                           Sharpless said.
            the  immune  system  to                                                                                             His  institute's  report  was
            make  antibodies  —  sub-                                                                                           posted on a website scien-
            stances  that  attach  to  a                                                                                        tists  use  to  share  research
            virus  and  help  it  be  elimi-                                                                                    and  is  under  review  at  a
            nated.                                                                                                              major medical journal.
            Researchers  found  that                                                                                            The findings are "not a sur-
            people    with   antibodies                                                                                         prise ... but it's really reassur-
            from    natural   infections                                                                                        ing because it tells people
            were "at much lower risk ...   FILE - This 2020 electron microscope image provided by the National Institute of Allergy and In-  that  immunity  to  the  virus
            on  the  order  of  the  same   fectious Diseases - Rocky Mountain Laboratories shows SARS-CoV-2 virus particles which cause   is  common,"  said  Joshua
                                         COVID-19, isolated from a patient in the U.S., emerging from the surface of cells cultured in a lab.
            kind  of  protection  you'd   According to two new studies released on Tuesday, Dec. 22, 2020, people who have antibodies   Wolf, an infectious disease
            get from an effective vac-   from infection with the coronavirus seem less likely to get a second infection for several months   specialist  at  St.  Jude  Chil-
            cine,"  of  getting  the  virus   and maybe longer. (NIAID-RML via AP)                                              dren's Research Hospital in
            again, said Dr. Ned Sharp-                                                                                          Memphis who had no role
            less, director of the U.S. Na-  of tests. One is a blood test  cine,  involved  more  than  symptoms.               in either study.
            tional Cancer Institute.     for  antibodies,  which  can  12,500  health  workers  at  That  contrasts  with  the  Antibodies themselves may
            "It's  very,  very  rare"  to  get  linger for many months af-  Oxford  University  Hospitals  11,364 workers who initially  not  be  giving  the  protec-
            reinfected, he said.         ter infection. The other type  in  the  United  Kingdom.  did  not  have  antibodies;  tion,  they  might  just  be  a
            The  institute's  study  had  of  test  uses  nasal  or  other  Among the 1,265 who had  223 of them tested positive  sign that other parts of the
            nothing to do with cancer  samples to detect the virus  coronavirus  antibodies  at  for  infection  in  the  roughly  immune  system,  such  as  T
            —  many  federal  research-  itself or bits of it, suggesting  the  outset,  only  two  had  six months that followed.  cells,  are  able  to  fight  off
            ers have shifted to corona-  current or recent infection.  positive  results  on  tests  to  The  National  Cancer  Insti-  any  new  exposures  to  the
            virus  work  because  of  the  One   study,   published  detect  active  infection  in  tute  study  involved  more  virus,  he  said.    "We  don't
            pandemic.                    Wednesday  by  the  New  the  following  six  months  than  3  million  people  who  know  how  long-lasting  this
            Both studies used two types  England  Journal  of  Medi-  and  neither  developed  had  antibody  tests  from  immunity is," Wolf added.q

             Russia cuts size of COVID-19 vaccine study, stops enrollment



                                                                      enrollment of volunteers.    Trials Organizations, said.  In  a  statement,  the  Health
                                                                      The decision comes a week  "They simply won't be able  Ministry  said  that  interim
                                                                      after  developers  said  en-  to  gather  (the  necessary)  study data on the vaccine's
                                                                      rollment of study volunteers  statistics," she said.      safety  and  effectiveness
                                                                      has slowed since Russia be-  Russia has been widely criti-  was  considered  as  part  of
                                                                      gan giving out the Sputnik  cized  for  giving  Sputnik  V  the decision to reduce the
                                                                      V  vaccine  while  the  late-  regulatory  approval  in  Au-  study size. The ministry said
                                                                      stage  study  was  still  con-  gust after the vaccine only  the  study  would  continue
                                                                      tinuing. They also cited ethi-  had been tested on a few  and  participants  will  be
                                                                      cal  concerns  about  giving  dozen  people.  Two  weeks  monitored  for  at  least  six
                                                                      a  dummy  shot  to  some  of  later, the 40,000-volunteeer  more months.
                                                                      the  volunteers.  The  study  study was announced.        Gintsburg  had  suggested
                                                                      size was cut to about 31,000  Despite warnings to wait for  giving  the  vaccine  to  all
                                                                      from 40,000 participants.    the  study's  results,  Russian  volunteers  who  received
                                                                      Alexander Gintsburg, head  authorities  started  offering  the  placebo  shot,  but  the
                                                                      of  the  Gamaleya  Center,  it  to  people  in  risk  groups  ministry  said  there  would
                                                                      the  state-run  medical  re-  —  such  as  medical  work-  be  no  "unblinding"  of  the
                                                                      search institute that devel-  ers  and  teachers  —  within  study at this point.
                                                                      oped  Sputnik  V,  said  that  weeks of approval.           In  other  words,  volunteers
                                                                      many  of  those  who  re-    President  Vladimir  Putin,  will  not  be  told  whether
                                                                      ceived  dummy  shots  had  who  has  publicly  hailed  they received real or dum-

            Russian  President  Vladimir  Putin  attends  a  meeting  via  video   figured  it  out  and  gotten  Sputnik V, ordered the Rus-  my vaccines.
            conference  in  Moscow,  Russia,  Wednesday,  Dec.  23,  2020.   vaccinated.           sian government this month  Kirill  Dmitriev,  head  of  the
            (Mikhail Klimentyev, Sputnik, Kremlin Pool Photo via AP)  If  large  numbers  of  volun-  to start a large-scale immu-  Russian  Direct  Investment
                                                                      teers in the placebo group  nization campaign. By mid-    Fund that bankrolled Sput-
            By  DARIA  LITVINOVA  Asso-  Wednesday to cut the size  drop out, it could affect the  December,  over  150,000  nik V, noted that U.S. drug-
            ciated Press                 of  a  study  of  a  domesti-  results,  Svetlana  Zavidova,  people  had  been  vacci-  maker  Johnson  &  Johnson
            MOSCOW  (AP)  —  Russia's  cally  developed  coronavi-    executive  director  of  Rus-  nated, according to Gints-  recently  reduced  the  size
            Health    Ministry   agreed  rus vaccine and to stop the  sia's  Association  of  Clinical  burg.                   of its vaccine trial. q
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