Page 705 - Equine Clinical Medicine, Surgery and Reproduction, 2nd Edition
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680                                        CHAPTER 3



  VetBooks.ir  3.134                                      The  severity of clinical signs varies considerably.
                                                          In the peracute disease form there is sudden death
                                                          due to pulmonary oedema. In the acute disease form
                                                          there is death from pulmonary oedema and myo-
                                                          cardial failure. In the subacute disease form there is
                                                          myocarditis with accompanying signs of heart failure
                                                          and death in around 50% of cases. The least severe
                                   Fig. 3.134             form of the disease (‘horse sickness fever’) occurs
                                   A veterinarian dressing   in horses with some immunity to the virus or in
                                   up to enter a stable with   resistant species (zebras and donkeys). In this form
                                   a horse that is suspected   there is transient URT disease and low mortality.
                                   to suffer from Hendra   Vaccination can be used to control the disease.
                                   virus. The personal
                                   protective equipment   Hendra virus
                                   for a suspected Hendra   Hendra virus (formally known as equine  morbil-
                                   case consists of a single   livirus) is a zoonotic henipavirus of the family
                                   use, full body coverage   Paramyxoviridae. Hendra virus infections in horses
                                   including a waterproof   and humans have been recognised since 1994 in
                                   suit with head cover,   Australia in Queensland and the north of New
                                   shoe covers, gloves,   South Wales. Hendra virus has a fruit bat reser-
                                   mask and glasses.      voir and transmission appears to require very close
                                                          contact with bat uterine secretions or  body fluid
           The rhinoviruses are shed through nasal secretions.   exposure from infected horses. Hendra virus infec-
           In addition, ERAV also sheds in faeces and urine.   tions  can  cause  fatal  pneumonia  and  encephalitis.
           ERAV causes viraemia, ERBV does not. Viral infec-  However, there are no pathognomic clinical signs, a
           tion can be confirmed with serology and PCR.   wide range of potential presenting clinical signs and
                                                          not all horses develop respiratory or neurological
           African horse sickness                         signs. This poses a significant challenge for attend-
           African horse sickness (AHS) is endemic in southern   ing veterinarians (Fig. 3.134). In the limited num-
           Africa and causes high morbidity and mortality in   ber of equine outbreaks that have occurred there has
           susceptible horses. It is a notifiable disease in many   been high morbidity and mortality, yet not all horses
           countries and is OIE listed. AHS is caused by an   die from the infection. Fatal infections of Australian
           orbivirus related to blue-tongue virus of sheep. The   equine veterinarians have occurred. Hendra virus
           virus requires an insect vector, Culicoides imicola, for   infection  is  a notifiable  disease  in Australia  and
           transmission. The geographical distribution of the   is OIE listed. Vaccination can be used to prevent
           vector extends into Europe and it is possible that cli-  the disease, and many equine referral hospitals in
           mate change may eventually extend its range further.   Queensland refuse unvaccinated horses.



           BACTERIAL DISEASE

           STRANGLES                                      draining the URT and a variety of other, potentially
                                                          fatal,  sequelae  including  disseminated  abscessation
           Definition/overview                            and purpura haemorrhagica. An alternative mani-
           Strangles is a highly contagious bacterial infection of   festation is a mild, transient URT disease without
           the URT, characterised in its most severe form (‘clas-  abscesses referred to as ‘atypical strangles’. In most
           sical strangles’) by abscessation of the lymph nodes   outbreaks the number of mild ‘atypical’ cases is
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