Page 918 - Equine Clinical Medicine, Surgery and Reproduction, 2nd Edition

Liver disease 893

VetBooks.ir (a) (b)

(c)

(d)

Fig. 5.18a–d Saponin-containing plants: (a) Lantana
camara (lantana) (Photo courtesy Forest & Kim
Starr); (b) Agave lechuguilla (agave); (c) Nolina texana
(bear grass); (d)Tribulus terrestris (puncture vine).

probably as a result of mycotoxins associated with of hepatic insult is often also seen in such cases
the plants rather than toxins inherent to the plants although the clinical signs of myopathy dominates.
themselves. Hypoglycin A toxicity associated with Drug-induced hepatotoxicity is rarely recognised
ingestion of seeds and seedlings from trees in the Acer in horses but must almost inevitably exist given the
genus (most notably Acer negundo and Acer pseudoplat- widespread use of agents well known to cause hepa-
anus) results in acute myopathy known as atypical totoxicity in other species. Agents used in equine
myopathy or seasonal pasture myopathy. Evidence medicine with the potential for hepatotoxicity