Page 550 - Fluid, Electrolyte, and Acid-Base Disorders in Small Animal Practice
P. 550

538        FLUID THERAPY












              I

                                                                                  Ao
                          150-                        Ao                 –100                                –100
              Ao
                      100-                   –100
                   50-
                0-
                                                                         –40
                                        45-
              PA                     30-     –30                                  PA                         –30

                                 15-
                                                      RV                                                     –0
                              0-                                         –0

                                                      RA                 –30
              RA                                                                  RA                         –5
                                             –10                         –15                                 –0
              A                                     B                          C
                        Figure 21-8 A, Electrocardiogram and pressure recordings from a standing dog with dilated
                        cardiomyopathy and biventricular cardiac dysfunction. There is pulmonary hypertension secondary to
                        abnormally high wedge pressure (not shown) and left-sided cardiac dysfunction. The pulmonary artery
                        pressures are approximately 39/23 (systolic/diastolic) mm Hg. The right atrial pressure (central venous
                        pressure) is also abnormally high, with a mean value of approximately 9 mm Hg. Scales indicate millimeters of
                        mercury for the adjacent curves. Ao, Pressure in the descending aorta; PA, pressure in the pulmonary artery;
                        RA, pressure in the right atrium. B, Electrocardiograph (ECG) and pressure recordings from a standing dog
                        with dilated cardiomyopathy and mitral and tricuspid regurgitation during infusion of 0.9% saline solution.
                        Volume expansion has led to a marked increase in the right atrial pressure (mean, 16 mm Hg). The right
                        ventricular pressure (RV) tracing also indicates an increase in the end-diastolic ventricular pressure (arrow).
                        Pulmonary hypertension from left-sided heart failure accounts for the increase in systolic RV pressure
                        (42 mm Hg, normal is <25 mm Hg). Scales on the right indicate millimeters of mercury for the preceding
                        curves. C, ECG and pressure recordings from a standing dog with mitral regurgitation and mild left-sided
                        heart failure. Pulmonary hypertension secondary to abnormally high wedge pressure (not shown) and left-
                        sided cardiac dysfunction are present. The pulmonary artery pressures are approximately 34/25 (systolic/
                        diastolic) mm Hg. The wedge pressure in this case was approximately 23 mm Hg. Despite the high left-sided
                        filling pressures, note that right atrial pressure is normal, with a mean (central venous pressure) value of
                        approximately 3 mm Hg. Scales on the right indicate millimeters of mercury for the preceding curves.

            with Doppler echocardiography, but requires specialized  3. Amberger CN, Glardon O, Glaus T, et al. Effects of
            equipment and training. The greatest value of this       benazepril in the treatment of feline hypertrophic cardio-
                                                                     myopathy: results of a prospective, open-label, multicenter
            technique is found in the following of trends, as the aortic
                                                                     clinical trial. J Vet Cardiol 1999;1:19–26.
            velocity-timeintegralincreases ordecreaseswithchanges in
                                                                   4. Asano K, Masuda K, Okumura M, et al. Plasma atrial and
            ventricular stroke volume.                               brain natriuretic peptide levels in dogs with congestive
                                                                     heart failure. J Vet Med Sci 1999;61:523–9.
                                                                   5. Atkins CE, Brown WA, Coats JR, et al. Effects of long-
            REFERENCES                                               term administration of enalapril on clinical indicators of
                                                                     renal function in dogs with compensated mitral regurgita-
                                                                     tion. J Am Vet Med Assoc 2003;221:654–8(Erratum inJ
              1. Abbott JA. Beta-blockade in the management of systolic  Am Vet Med Assoc 2002;15:1149 221.
                dysfunction. Vet Clin North Am Small Anim Pract    6. Atkins  CE, Keene  BW,  Brown  WA, Coats  JR,
                2004;34:1157–70.                                     Crawford MA, DeFrancesco TC, et al. Results of the vet-
              2. Adin DB, Taylor AW, Hill RC, et al. Intermittent bolus  erinary enalapril trial to prove reduction in onset of heart
                injection versus continuous infusion of furosemide in nor-  failure in dogs chronically treated with enalapril alone for
                mal  adult  greyhound  dogs.  J  Vet  Intern  Med    compensated, naturally occurring mitral valve insuffi-
                2003;17:632–6.                                       ciency. J Am Vet Med Assoc 2007;231(7):1061–9.
   545   546   547   548   549   550   551   552   553   554   555