Page 470 - Feline diagnostic imaging
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482  27  Urinary Disease
            fibrinohemorrhagic  tissue  adhering  to  a  thickened   27.4.4  Neoplasia
              bladder wall. The urine contained a fibrinous exudate,   The most common neoplasm in the urinary bladder is tran-
            blood clots, necrotic and suppurative material, and focal
            mineralization. The sonographic appearance was simi-  sitional cell carcinoma (Figure 27.33) but other neoplasms
                                                              occur,  such  as  lymphosarcoma  (Figure  27.34)  [41].
            lar in the four cats: the bladder had a thickened wall and
            appeared compartmentalized because of septae crossing   Transitional cell carcinoma is less likely to be at the trigone
                                                              in cats than in dogs. In one study, 55% of 20 neoplasms had
            the  lumen.  Bladder  contents  were  echogenic.  Double
            contrast  cystography  in  one  cat  revealed  a  thickened   a location other than the trigone [42]. In another, only 3/11
                                                              cats  had  transitional  cell  carcinoma  at  the  trigone  [43].
            bladder wall and a lumen contained a large amount of
            solid material.                                   Neoplasia  is  rarely  detectable  on  survey  radiography.
                                                              Bladder masses are painful, resulting in frequent urination
              Severe cystitis and polyploid cystitis can resemble neopla-
            sia. Traumatic catheterization or endoscopy can be used to   and a normal‐sized bladder. Rarely, mineralization in the
                                                              bladder  wall  may  signal  the  presence  of  neoplasia.
            help differentiate these conditions. Most, but not all, polyps
            are associated with transitional cell carcinoma. Blood clots   Additionally, there may be evidence of metastasis to other
                                                              organs including lymph nodes, lungs, and bone.
            can be mistaken for masses within the bladder. Repositioning
                                                                Double contrast cystography is the preferred contrast pro-
            the patient can help show that a clot is not associated with   cedure  for  evaluation  of  suspected  neoplasia.  The  mass
            the bladder wall but some blood clots adhere to the bladder
            wall and are more difficult to differentiate. Those free in the   shows as a filling defect when it is on the dependent side but
                                                              it will be coated with contrast on the nondependent side.
            lumen  can  be  mistaken  for  calculi. When  hemorrhage  is
            present in the bladder, the bladder should be gently flushed   The neoplasm usually presents as a polyploid mass but in
                                                              some cases, there is severe mural thickening. Hydronephrosis
            with saline to help remove blood clots.



             (a)                                                                                          (b)



















                                        (c)



















            Figure 27.33  Ultrasonography of transitional cell carcinoma in a 17-year-old domestic longhair. (a) A polyp measuring 0.82 × 1.43 cm
            extends from the bladder wall. (b) Another scan through a different plane shows marked polyploid thickening of the visible bladder
            wall with a loss of wall layering. (c) Transitional cell carcinoma usually involves the apex of the urinary bladder in cats, unlike in dogs
            where the trigone is likely to be involved. In this image, a polyp can be seen extending into the lumen but the trigone is not affected.
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