Page 1182 - Cote clinical veterinary advisor dogs and cats 4th
P. 1182

Lipoma   591


               0.6 mg/kg IV q 24h, or metoclopramide    PROGNOSIS & OUTCOME       of cats actively sought out lilies that owners
               0.1-0.5 mg/kg SQ q 6-12h.       •  If treatment is initiated within 18 hours of   had attempted to keep out of reach.
  VetBooks.ir  with opiates such as buprenorphine   ingestion, before onset of oliguria or uremic   Technician Tips   Diseases and   Disorders
             ○   Abdominal pain can be managed
               0.01-0.03 mg/kg IM, IV, buccal q 6-12h.
                                                signs (from AKI), prognosis is good.
                                                                                  Some florists believe that plucking stamens out
             ○   Peritoneal dialysis or hemodialysis if
               oliguria/anuria develops; renal transplan-  •  Prognosis  after  onset  of  oliguria/anuria/  of lily flowers renders them nontoxic, which is
                                                                                  incorrect. Therefore, any part of the lily plant
                                                uremic signs is guarded to poor.
               tation can be considered if response is                            in vomitus should be considered evidence of
               positive.                        PEARLS & CONSIDERATIONS           potentially toxic exposure.
             ○   Control seizures with diazepam 0.5-2 mg/
               kg IV prn.                      Comments                           Client Education
                                               •  Even when vomiting is mild and self-limited,   Clients should ensure plants are nontoxic before
           Recommended Monitoring               the presence of plant material in vomitus   bringing them into environments with cats.
           •  Serum biochemistry profile baseline, 24, 48,   makes it critical to initiate treatment, includ-
             and 72 hours (especially electrolytes and renal   ing IV fluids, to minimize AKI.  SUGGESTED READING
             values). Recheck BUN and creatinine daily   •  Lily  toxicosis  should  be  high  on  the  dif-  Hall JO: Lilies. In Peterson ME, et al, editors: Small
             during clinical syndrome or for 72 hours if   ferential diagnosis list for any cat with AKI   animal toxicology, ed 3, St. Louis, 2013, Saunders,
             no abnormalities are seen.         and an extremely high serum creatinine     pp 617-620.
           •  Urinalysis  (baseline,  24,  48,  72  hours):   level.              AUTHOR: Sharon M. Gwaltney-Brant, DVM, PhD,
             ensure isosthenuria/hyposthenuria as sign   •  Neither lily-of-the-valley (Convallaria majalis)   DABVT, DABT
             of adequate fluid diuresis.        nor peace lily (Spathiphyllum spp) causes AKI   EDITOR: Tina Wismer, DVM, MS, DABVT, DABT
           •  If azotemia develops, monitor urine output.  in cats because they are not true lilies.
           •  Monitor for fluid overload: respiratory rate
             and character, onset of gallop sound on   Prevention
             cardiac auscultation, central venous pressure   Do not keep any Lilium or Hemerocallis species
             if possible.                      in environments with cats. In one study, 27%




            Lipoma                                                                                 Client Education
                                                                                                          Sheet


            BASIC INFORMATION                  •  Occasionally,  a  large  lipoma  (especially   Differential Diagnosis
                                                intrathoracic or intraabdominal) may cause   •  Subcutaneous mast cell tumors can appear
           Definition                           clinical signs due to space-occupying effects.  identical  on  physical  exam;  cytologic
           Benign tumor of mature fat cells/adipocytes;   •  Rarely, systemic signs of illness are caused by   evaluation readily distinguishes them from
           very common                          torsion of a lipoma’s vascular pedicle, creating   lipomas.
                                                a necrotic center and causing bacteremia/  •  Lipomas  can  appear  firm  on  palpation  if
           Epidemiology                         systemic inflammation.              they develop deep to underlying muscle
           SPECIES, AGE, SEX                                                        or fascia and may be confused with other
           Occurs most commonly in older dogs, less   PHYSICAL EXAM FINDINGS        subcutaneous tumors such as soft-tissue
           frequently in older cats            •  Solitary or multiple subcutaneous, nonpain-  sarcomas.
                                                ful, movable masses of variable sizes and   •  A lipoma may be mistaken for a more biologi-
           Clinical Presentation                shapes; often soft but may be firm  cally harmful mass (especially intrathoracic
           DISEASE FORMS/SUBTYPES              •  Intermuscular  lipoma:  palpable  mass  in   or abdominal).
           •  Subcutaneous: most common         caudal thigh (typically between semimem-
           •  Intermuscular                     branous and semitendinosus fascial planes)  Initial Database
           •  Intrathoracic or intraabdominal  •  Other locations (when accessible on exam):   Fine-needle aspiration and cytologic evaluation
           •  Infiltrative: locally invasive into surrounding   palpable, nonpainful mass  reveal adipocytes.
             tissue
           •  Necrotic                         Etiology and Pathophysiology       Advanced or Confirmatory Testing
           •  Myelolipoma: rare, benign tumor composed   •  Benign  tumor  of  adipocytes  that  grows   •  Ultrasound  echotexture  consistent  with
             of well-differentiated adipocytes and hema-  by  expansion  rather  than  by  invasion;   fat: highly suggestive that an abdominal or
             topoietic  cells;  spleen,  adrenal  gland,  and   nonmetastatic       intrathoracic mass may be a lipoma
             liver most common sites           •  Medical significance, if any, generally arises   •  CT  may  be  required  for  infiltrative  or
           •  Liposarcoma: uncommon neoplasm arising   from the physical presence of the mass, which   intermuscular lipomas to help determine
             from  lipoblasts  and  mesenchymal  tissue;   can interfere with ambulation or internal   full extent of tumor.
             cytologically characterized by spindle cells   organ function.         ○   Fat-opacity mass that infiltrates surround-
             and immature adipocytes; low metastatic rate;                            ing tissue, sometimes with fine linear stria-
             malignant transformation from lipomas has    DIAGNOSIS                   tions in infiltrated muscle; differentiation
             not been reported                                                        of infiltrative lipoma from adjacent normal
                                               Diagnostic Overview                    subcutaneous fat is difficult.
           HISTORY, CHIEF COMPLAINT            The diagnosis is suspected when aspiration of a   ○   No evidence of metastasis
           •  Generally incidental finding as reported by   soft subcutaneous mass is performed and cyto-  •  Definitive diagnosis of lipoma (and exclusion
             the owner or during the course of a routine   logic evaluation yields only well-differentiated   of other tumor types) requires histopathologic
             physical exam                     adipocytes.                          exam of tissue.

                                                      www.ExpertConsult.com
   1177   1178   1179   1180   1181   1182   1183   1184   1185   1186   1187