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Anal Sac Diseases   53




            Anal Sac Diseases                                                                      Client Education
                                                                                                          Sheet
  VetBooks.ir                                                                     Acute General Treatment             Diseases and   Disorders

                                               •  Anal sac mass
            BASIC INFORMATION
                                               •  Others possible with anal sac neoplasia  •  Anal sac impaction: expression of anal sac
           Definition                                                               contents is often sufficient to alleviate clinical
           Diseases of the anal sacs, the most   Etiology and Pathophysiology       signs, although recurrence is not unusual.
           clinically important of which are impaction,   The underlying cause of impaction and   Sedation and lavage of anal sacs with saline
           inflammatory/infectious, or neoplastic (primar-  inflammatory/infectious  anal  sac  disease  is   may be needed in some animals to soften
           ily adenocarcinoma). Information on neoplastic   unknown. Some speculated causes include   secretions for easier expression.
           anal sac disease can be found on (p. 29).  retention of anal sac secretions or abnormal   •  Anal sacculitis: typical approach to treatment
                                               composition of secretions leading to bacterial   is expression of anal sac followed by infusion
           Synonyms                            colonization and inflammation or impaction.   of antibiotic/glucocorticoid-containing oint-
           Anal sacculitis, anal sac impaction, anal sac   Experimental models that occlude the anal sac   ments (otic or ophthalmic products) through
           abscess, adenocarcinoma of the apocrine glands   duct or establish infection have not consistently   the anal sac duct into the anal sac. Lavage of
           of the anal sac                     reproduced features of the clinical disease.  anal sacs, perhaps with ceruminolytic agents,
                                                                                    may be helpful in severe cases.
           Epidemiology                                                           •  Anal  sac  abscess:  therapy  as  described  for
           SPECIES, AGE, SEX                    DIAGNOSIS                           anal sacculitis and also systemically admin-
           Dogs are affected with anal sac disease more   Diagnostic Overview       istered antimicrobials, typically those with
           often than cats. There is no sex predisposition   The diagnosis of anal sac disease is based primarily   a gram-positive spectrum such as beta-lactams
           to inflammatory anal sac disease.   on clinical signs and physical examination find-  (e.g., cephalosporins, amoxicillin-clavulanic
                                               ings of anal sac distention, pain or discomfort,   acid), or clindamycin. Drainage (lance and
           GENETICS, BREED PREDISPOSITION      or a mass during examination of the anal sacs.  lavage) may be needed in some. Antibiotics
           Small-breed dogs that typically weigh < 15 kg                            often continued for 2-3 weeks to the point
           may be at increased risk for impaction. Miniature   Differential Diagnosis  of no further signs of infection.
           and toy poodles, Chihuahuas, American cocker   •  Other causes of tenesmus or hematochezia
           spaniels, and English springer spaniels have   ○   Acute or chronic colitis  Chronic Treatment
           been singled out as at-risk breeds. Increased   ○   Rectal masses      Patients with recurrent anal sac impaction or
           risk of infection in Siamese cats has been     ○   Perianal fistula    infection may be candidates for anal sacculec-
           suggested.                          •  Other  causes  of  perianal  pruritus  and   tomy or anal sac marsupialization to achieve
                                                inflammation                      long-term resolution of disease.
           RISK FACTORS                         ○   Allergic skin disease
           Obesity;  diarrhea  or  chronic  soft  stools   ○   Food allergy       Nutrition/Diet
           (impaction); seborrheic disorders (impaction);   ○   Flea allergy dermatitis  Some clinicians advocate adding fiber to the
           routine expression of anal sacs in normal dogs   ○   Parasitic skin disease  diet or changing diets in patients with soft/
           has been suggested to pose a risk of inadver-  ○   Perianal pyoderma   loose  stools  to  produce  a  stool  quality  that
           tent anal sac trauma and recurrent anal sac     ○   Tail fold or perivulvar dermatitis  promotes emptying of anal sacs during defeca-
           disease.                                                               tion, but the role of diet in management of
                                               Initial Database                   anal sac disease has not been explored.
           Clinical Presentation               Results  of  a  CBC,  biochemical  profile,  and
           DISEASE FORMS/SUBTYPES              urinalysis are nonspecific. In severe cases, there   Possible Complications
           Clinical  features  may  reflect  those  of  the   can be an inflammatory leukogram.  Potential complications of anal sac surgery
           primary anal sac disease or distant/systemic                           include fecal incontinence or fistulas if the anal
           consequences of anal sac neoplasia (p. 29).  Advanced or Confirmatory Testing  sac is incompletely resected.
                                               •  There are no specific cytologic features that
           HISTORY, CHIEF COMPLAINT             suggest the diagnosis. Clinically normal   Recommended Monitoring
           Most affected animals present with one or more   dogs can have intracellular and extracellular   Clinical signs; serial microscopic examination
           of the following:                    bacteria and leukocytes in anal sac secre-  of anal sac secretions to document decreasing
           •  Scooting                          tions. In conjunction with clinical signs,   intracellular bacterial numbers and erythrocytes
           •  Licking or chewing at perianal region  large numbers of intracellular bacteria and   may be considered, but is not routinely done.
           •  Reluctance to sit or lift tail    erythrocytes seen on cytologic examination
           •  Tenesmus or painful defecation    of anal sac contents support a diagnosis of    PROGNOSIS & OUTCOME
           •  Fresh blood on stool              anal sac infection.
           •  Others possible with anal sac neoplasia  •  Skin scrapes, diet trials, or other skin-specific   The prognosis for most patients with anal sac
                                                approaches may be needed in patients with   disease  is  good  to  excellent  with  treatment.
           PHYSICAL EXAM FINDINGS               clinical signs that persist after treatment of   Persistence  of clinical  signs  can provoke
           Physical examination abnormalities are typically   anal sac disease or that have obvious features   investigation into other causes of colonic or
           limited to the perianal region:      of dermatoses.                    perianal skin disease.
           •  Anal sac distention
           •  Pain during rectal examination    TREATMENT                          PEARLS & CONSIDERATIONS
           •  Bloody anal sac contents
           •  Loss of hair, redness, perianal swelling and   Treatment Overview   Comments
             pain in tissues overlying anal sac (abscess)  Treatment is largely directed at expressing anal   Rectal  examinations  should  be  performed
           •  Draining tract (abscess)         sac contents (impaction) and treating infection   as a part of routine physical examinations
           •  Fever (abscess)                  (sacculitis or abscess).           on dogs for early detection of anal sac masses.

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