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Pneumonia, Aspiration   793


           •  Retrosternal fat and interindividual variation   with handling. Minimal handling is    develops a tachypnea or increased effort after
             may give the false impression of pleural   •  Supplemental oxygen should be provided to   pleural drainage, alert the attending clinician
                                                important.
  VetBooks.ir  of animals without pleural effusion. For this   •  Avoid dorsal recumbence (ventrodorsal view)   SUGGESTED READING  Diseases and   Disorders
             effusion on lateral radiographic projections
                                                                                    as soon as possible.
                                                all dyspneic patients.
             reason and to determine whether effusion
             is unilateral or bilateral, a minimum of
                                                effusions.
             two-view thoracic radiographs is indicated.  for radiographs in animals with pleural   Dempsey SM, et al. A review of the pathophysiol-
                                                                                   ogy,  classification,  and  analysis  of canine  and
                                               •  Supplies  for  emergency  thoracocentesis:   feline cavitary effusions. J Am Anim Hosp Assoc
           Prevention                           clippers, skin preparation materials, butterfly   47:1-11, 2011.
           Avoid trauma and exposure to anticoagulant   needle or needle with an extension set, 3-way   AUTHOR: Graham Swinney, BVSc, DVCS, FANZCVS
           rodenticides.                        stopcock, and syringes            EDITOR: Megan Grobman, DVM, MS, DACVIM
                                               •  Complications of thoracocentesis (e.g., pneu-
           Technician Tips                      mothorax, hemothorax): if patient suddenly
           •  Animals  with  large-volume  pleural  effu-
             sions are fragile and susceptible to stress



            Pneumonia, Aspiration                                                                  Client Education
                                                                                                          Sheet


            BASIC INFORMATION                  •  Pneumothorax                    •  Gastric contents are typically sterile, but acid
                                               •  Shock                             and particulate matter can cause potentially
           Definition                          •  Airway obstruction                severe damage.
           •  Infection  associated  with  inhalation  of   Clinical Presentation   ○   Acid causes direct, caustic epithelial injury
             oropharyngeal secretions, foodstuffs, other                              that is followed by inflammation.
             foreign material, or gastric contents  DISEASE FORMS/SUBTYPES          ○   Particulate material may obstruct airways.
           •  In  veterinary  medicine,  the  term  is  often   •  Acute or chronic  •  Infection  may  follow  aspiration  of  con-
             used in reference to aspiration pneumo-  •  Fulminant or insidious     taminated oropharyngeal secretions or as a
             nitis, which is chemical injury caused by                              secondary (opportunistic) complication of
             inhalation of gastric contents (most com-  HISTORY, CHIEF COMPLAINT    respiratory damage.
             monly) or other materials (e.g., barium,     Clinical signs may be absent or severe; when   Severity of injury depends on volume, toxicity,
             mineral oil).                     present, they may include          pH, particulates, and pathogen content of
                                               •  Anorexia                        aspirated material. Sequelae may include
           Synonym                             •  Collapse                        •  Airway obstruction
           Aspiration pneumonitis              •  Cough                           •  Bronchoconstriction
                                               •  Lethargy                        •  Pulmonary hemorrhage
           Epidemiology                        •  Respiratory distress            •  Epithelial necrosis
           SPECIES, AGE, SEX                   •  Others that reflect predisposing cause (e.g.,   •  Pulmonary inflammation or edema
           Most often male dogs, but dogs (and less often,   regurgitation, anesthetic episode)
           cats) of either sex and any age                                         DIAGNOSIS
                                               PHYSICAL EXAM FINDINGS
           GENETICS, BREED PREDISPOSITION      Findings may be absent or severe; when present,   Diagnostic Overview
           Large breeds of dogs are overrepresented. Irish   they may include:    Differentiation of aspiration pneumonia from
           wolfhound may be predisposed.       •  Tachypnea                       bacterial pneumonia or pulmonary edema
                                               •  Cough                           often depends on circumstantial evidence
           RISK FACTORS                        •  Inspiratory and expiratory distress  such as history of vomiting or regurgitation
           •  Diseases of                      •  Auscultatory abnormalities (may be localized   or involvement of the typical dependant lung
             ○   Pharynx or larynx (e.g., laryngeal paralysis,   if present)      lobes.
               before and after arytenoid lateralization;   ○   Increased or harsh bronchovesicular sounds
               extraesophageal reflux)            (≈50%)                          Differential Diagnosis
             ○   Esophagus (e.g., megaesophagus, severe   ○   Decreased bronchovesicular sounds (≈6%)  •  Infectious pneumonia
               esophagitis)                     ○   Crackles (≈10%)               •  Cardiogenic or noncardiogenic pulmonary
             ○   Stomach or intestine (e.g., pyloric or upper   ○   Wheezes (≈2%)   edema
               intestinal obstruction)         •  Cyanosis (rare)                 •  Neoplastic infiltrates
           •  Forced  enteral  administration  of  drugs  or   •  Fever (<50% are febrile)
             foods                             •  Shock (rare)                    Initial Database
           •  Impaired protective reflexes (e.g., anesthesia,   •  Others  that  reflect  predisposing  cause   •  Neurologic exam (p. 1136) reflects underly-
             seizure)                           (e.g., exercise intolerance with myasthenia   ing neurologic disease, if present.
                                                gravis–related megaesophagus)     •  CBC: neutrophilic leukocytosis ± left shift
           ASSOCIATED DISORDERS                                                     common
           •  Acute respiratory distress syndrome  Etiology and Pathophysiology   •  Serum  biochemical  profile  and  urinalysis:
           •  Bacterial pneumonia              Inhalation of particulates or fluid into the   no specific changes
           •  Hypoxemia                        larynx and lower respiratory tract triggers     •  Thoracic radiographs: abnormalities may lag
           •  Lung lobe abscessation           injury.                              aspiration event by up to 24 hours

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