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Pseudocyesis   831


           trials, the most effective treatment regimen   •  For  food  hypersensitivity,  clinicians  must   •  If pruritus is refractory to a usual mainte-
           that is available  and safe should be used to   find a commercial hypoallergenic diet that   nance dose of glucocorticoid (i.e., > 0.5 mg/
  VetBooks.ir  of response is clear.           •  In  flea  bite  hypersensitivity,  maintain  an   the following diagnoses: sarcoptic mange,   Diseases and   Disorders
                                                                                    kg q 48h of prednisone in dogs), consider
                                                maintains the animal free of clinical signs
           eradicate parasites or infections so interpretation
                                                (p. 345).
                                                                                    Malassezia dermatitis, pyoderma, food hyper-
           Acute General Treatment
           An acute, intense pruritic episode can be treated   effective flea elimination treatment (p. 342).  sensitivity, calcinosis cutis, contact allergic
                                                                                    dermatitis, and epitheliotropic lymphoma.
           with IM or IV short-acting glucocorticoids   Recommended Monitoring    •  More than one disease may be contributing
           (dexamethasone sodium phosphate 0.1-0.2 mg/  Animals receiving chronic glucocorticoid   to pruritus; for example, dogs with atopic
           kg), followed by a few days of prednisone or   therapy should be monitored every 6 months   dermatitis often have secondary bacterial and/
           prednisolone 1 mg/kg PO q 24h. Short-term   for  signs  of  iatrogenic  hyperadrenocorticism   or yeast infections.
           use of glucocorticoids seldom causes serious   or other complications (e.g., urinary tract
           problems. Oclacitinb (Apoquel) can be an   infection, pyoderma, weight gain).  Technician Tips
           alternative in such cases.                                             Explain to the owner how to quantify the
                                                PROGNOSIS & OUTCOME               pruritus level using a validated pruritus
           Chronic Treatment                                                      severity  scale  (http://www.cavd.ca/images/
           •  In  long-term  management  of  pruritus,   •  Varies according to the cause  CAVD_ITCH_SCALE.pdf).
             as in cases of canine atopic dermatitis (p.   •  Excellent for most parasitic and infectious
             91), clinicians rely on immunotherapy   skin problems and food hypersensitivity  Client Education
             (hyposensitization), glucocorticoids, oral   •  Atopic dermatitis is an incurable disease that   •  Owners of dogs with canine atopic dermatitis
             cyclosporine (Atopica), oclacitinib, interleukin-   requires long-term management of pruritus.  must be well informed about the chronic
             31caninized  monoclonal  antibodies  (Cyto-                            and multifaceted nature of the disease.
             point), antihistamines, and/or essential fatty    PEARLS & CONSIDERATIONS  •  A pruritus score (http://www.cavd.ca/images/
             acid supplementation.                                                  CAVD_ITCH_SCALE.pdf) is very useful for
           •  Long-term administration of glucocorticoids   Comments                evaluating response to treatment or disease
             should be avoided, unless the maintenance   •  Treatment of pruritic dermatoses does not   progression. It adds a measure of objectivity
             dose is low (e.g., < 0.25 mg/kg of prednisone   always imply use of antipruritic drugs specifi-  and may reduce the owner’s perception that
             q 48-72h in dogs) and/or if the treatment   cally. Antiparasitic drugs, antibiotics, and   treatment is ineffective or may support the
             is intermittent.  In dogs,  induction  and   antifungal drugs (for yeast dermatitis), which   severity of pruritus perceived by the owner.
             maintenance doses of prednisolone are typi-  are not inherently antipruritic, are among the
             cally  ≈30%  lower  than  prednisone  doses,   most useful antipruritic drugs. They have a   SUGGESTED READING
             at  least  when  administered  concomitantly   key role in pruritus management because they   Tater KC: An approach to pruritus. In Jackson H,
             with trimeprazine (Temaril-P,  Vanectyl-P   control or eliminate the underlying cause.   et al, editors: BSAVA manual of canine and feline
             [Canada]). A long-term treatment goal with   Superficial pyoderma is a frequent cause of   dermatology, ed 3, Gloucester, 2012, British Small
             these combination products is to administer   pruritus in dogs.       Animal Veterinary Association, pp 37-45.
             the minimal effective dose q 48h.  •  Always rule out parasitic and infectious causes   AUTHOR & EDITOR: Manon Paradis, DMV, MVSc,
           •  In cats, prednisone is generally not effective.   of pruritus before administering long-term   DACVD
             Oral  prednisolone,  methylprednisolone,   antipruritic drugs or before initiating an
             dexamethasone, or triamcinolone is preferred.  elimination diet (food trial).




            Pseudocyesis



            BASIC INFORMATION                  •  German  shepherds  and  beagles  are  rarely   HISTORY, CHIEF COMPLAINT
                                                affected.                         •  Estrus 6-12 weeks before, without ensuing
           Definition                                                               pregnancy
           The common syndrome observed in nonpregnant   RISK FACTORS             •  Chief  complaints:  mammary  problems
           diestrous or early anestrous bitches is character-  Exogenous administration of progestins,   (engorgement, lactation, licking of the
           ized by different degrees of maternal behavior,   diestrous ovariectomy, and/or hypothyroidism   glands)  and  abnormalities  associated  with
           mammary gland enlargement, and lactation.  may trigger its occurrence.   aberrant maternal behavior (nesting, digging,
                                                                                    adoption of animals or objects)
           Synonyms                            ASSOCIATED DISORDERS               •  Depression or anxiety, anorexia, and excessive
           Nervous anorexia, pseudopregnancy, overt false   May predispose to mastitis  vocalization (whining) are possible.
           pregnancy
                                               Clinical Presentation              PHYSICAL EXAM FINDINGS
           Epidemiology                        DISEASE FORMS/SUBTYPES             •  Mammary  enlargement,  ranging  from
           SPECIES, AGE, SEX                   Depends on intensity of clinical signs:  turgid nipples to painful engorgement and
           Postpubertal female dogs of any age; has not   •  Covert: physiologic, although recognizable   galactostasis, is most evident in the caudal
           been described in cats               from the rest of the estrous cycle  pair of glands.
                                               •  Overt:  physical  and  behavioral  manifesta-  •  Mammary dermatitis occasionally occurs if
           GENETICS, BREED PREDISPOSITION       tions become a clinical problem (clinical   excessive licking occurs.
           •  Any breed; incidence is higher among Dal-  pseudocyesis)
             matians, basset hounds, and pointer-breed
             dogs.

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