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Restrictive Cardiomyopathy, Feline   881


           Advanced or Confirmatory Testing    diagnostic testing to control respiratory crisis    PROGNOSIS & OUTCOME
           Choice of tests depends on prior results but   (e.g.,  thoracocentesis  to  remove  fluid  or  air,   Depends on underlying disease process and
  VetBooks.ir  •  Oral/pharyngeal  exam:  may  require  seda-  bypass  laryngeal  obstruction).  The  eventual   severity  Diseases and   Disorders
                                               endotracheal  intubation  or  tracheostomy  to
           often includes
                                               goal is to address the underlying cause.
             tion;  evaluate  above  the  soft  palate  (e.g.,
             nasopharyngeal polyps) and below the
             tongue                            Acute General Treatment             PEARLS & CONSIDERATIONS
           •  Laryngeal function exam (p. 574)  •  Oxygen supplementation (p. 1146)  Comments
           •  Plasma  N-terminal  pro-brain-type  natri-  •  Specific  treatments  depend  on  underlying   Patients in respiratory distress are fragile and
             uretic  peptide  (NT-pro-BNP)  may  be   cause.                      prone to decompensation. Avoid excessive
             increased in disease of cardiac origin such   ○   Upper airway obstruction: ensure   handling and restraint.
             as congestive heart failure (CHF) (pp. 408    patency  of  the  airway  (e.g.,  endotra-
             and 1369).                           cheal  tube;  tracheostomy  [p.  1166]),   Technician Tips
           •  Echocardiography (pp. 408 and 838): CHF   sedation  (p.  574),  external  cooling  as    Provide supplemental oxygen to any animal
             and pulmonary hypertension           needed                          with  respiratory  distress.  Minimize  handling
           •  Arterial  blood  gas  (p.  1058);  if  can  be   ○   Lower  airway  obstruction:  sedation,   and stress. Animals in respiratory distress may
             obtained without additional distress, allows   bronchodilators (p. 84)  bite when handled.
                                                ○   CHF: diuretics (p. 408)
             accurate assessment of O 2, CO 2
           •  Respiratory  fluoroscopy:  dynamic  airway   ○   Pleural effusion, pneumothorax: thoraco-  Client Education
             collapse/obstruction (e.g., tracheal collapse,   centesis (p. 1164)  •  Sustained  open-mouth  breathing  is  never
             mainstem  bronchial  collapse,  epiglottic   ○   Address abdominal distention (e.g., ascites,   normal in a cat and should prompt veterinary
             retroversion)                        bloat).                           assessment.
           •  Thoracic  CT  can  be  performed  quickly   ○   Positive-pressure ventilation may become   •  At home resting respiratory rates can help
             and provides more detail than thoracic   necessary, typically when PaO 2  < 60 mm   monitor for disease progression.
             radiographs.                         Hg or PaCO 2  > 60 mm Hg despite oxygen
           •  Bronchoscopy with bronchoalveolar lavage   supplementation (p. 1185).  SUGGESTED READING
             for culture and cytology (p. 1073)                                   Sumner C, et al: Management of respiratory emergen-
           •  Bronchoalveolar lavage (blind) or transtra-  Possible Complications  cies in small animals. Vet Clin North Am Small
             cheal wash (p. 1073)              Uncontrolled respiratory distress may lead to   Anim Pract 43:4, 2013.
           •  Diagnosis of interstitial lung diseases (p. 553)   progressive  hypoxemia,  cyanosis,  respiratory   AUTHOR: Megan Grobman, DVM, MS, DACVIM
             might require lung biopsy.        fatigue, and death.                EDITOR: Leah A. Cohn, DVM, PhD, DACVIM
           •  Infectious disease testing, as appropriate
                                               Recommended Monitoring
            TREATMENT                          During period of respiratory distress, frequent
                                               monitoring  of  respiratory  effort  and  rate  is
           Treatment Overview                  essential. Pulse oximetry and/or arterial blood
           Provide oxygen supplementation immediately.   gas analysis allow assessment of oxygenation.
           Specific intervention may be necessary before   Thoracic imaging may need to be repeated.









            Restrictive Cardiomyopathy, Feline                                                     Client Education
                                                                                                          Sheet


            BASIC INFORMATION                  Synonyms                           •  Middle- to older-aged cats are most often
                                               End-stage   hypertrophic   cardiomyopathy   affected, although RCM has been reported
           Definition                          (HCM) and unclassified cardiomyopathy   in cats as young as 4 months of age to as
           Restrictive cardiomyopathy (RCM) is a primary   (UCM) are difficult to differentiate from each   old as 19 years. Varied sex predisposition has
           myocardial disease that occurs more commonly   other and from RCM. UCM and end-stage   been reported with no apparent consensus.
           in cats than dogs. It is characterized by impaired   HCM are characterized by severe left atrial
           ventricular filling, severe biatrial enlargement,   or  biatrial  enlargement;  mixed  changes  to   GENETICS, BREED PREDISPOSITION
           normal (nonhypertrophied) ventricular wall   the  ventricles,  including  areas  of  thickening   RCM has been described in many cat breeds,
           thickness,  normal  (nondilated)  ventricular   and  areas  of  thinning  (scarring);  ventricular   with possible predominance in domestic
           chamber size, and normal to mildly reduced   dilatation; and depressed systolic function.  shorthair, Siamese, Persian, and Burmese.
           systolic function in the absence of valvular   Epidemiology
           lesions. Some classification schemes also                              ASSOCIATED DISORDERS
           consider RCM to be characterized by normal   SPECIES, AGE, SEX         •  Acute  and  chronic  left  or  biventricular
           to mildly thickened ventricular myocardium.   •  RCM  is  reported  to  be  the  second  most   congestive heart failure (CHF)
           In unclassified cardiomyopathy, the echocar-  common cardiomyopathy in cats, although   •  Arterial thromboembolism (ATE): may be
           diographic anatomic changes are similar, but   true prevalence is difficult to determine given   more common with RCM than HCM
           ventricular filling cannot be assessed (i.e., due   the inconsistent diagnostic characterizations   •  Syncope/sudden  cardiac  death:  typically
           to heart rate).                      used previously.                    arrhythmogenic

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