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Splenic Torsion   935


            PEARLS & CONSIDERATIONS            •  Significantly  lower  serum  vitamin  D   State University Veterinary Clinical Pharmacol-
                                                concentrations in dogs with  Spirocerca   ogy Lab (https://vcpl.vetmed.wsu.edu/).
           Comments
  VetBooks.ir  •  In North America and Europe, spirocercosis   with esophageal neoplasia) may offer new   SUGGESTED READING  Diseases and   Disorders
                                                granulomas (and even lower levels in those
             is a rare disease and is considered only when
                                                insights in the mechanism and/or treatment
                                                                                  Lobetti  R:  Successful  resolution  of  oesophageal
             there is a high index of clinical suspicion.
           •  The characteristic lesion is a soft-tissue mass   of spirocercosis.  spirocercosis in 20 dogs following daily treatment
                                                                                   with oral doramectin. Vet J 193(1):277-278, 2012.
             in the caudal esophagus; radiographically   Prevention               AUTHOR: Steven L. Marks, BVSc, MS, DACVIM
             and clinically, foreign-body ingestion is an   Prevent dogs from eating beetles or paratenic   EDITOR: Rance K. Sellon, DVM, PhD, DACVIM
             important differential diagnosis.  hosts.
           •  A  minority  of  dogs  develops  neoplastic
             transformation of esophageal granulomas   Technician Tips
             (e.g., 13 of 14 dogs with spirocercosis had   Testing for the MDR1/ABCB1-Δ mutation is
             esophageal  masses,  but  only  1  of  13  had   easily accomplished by submitting an EDTA
             esophageal neoplasia).            blood sample or cheek swab to the Washington






            Splenic Torsion                                                                        Client Education
                                                                                                          Sheet


            BASIC INFORMATION                  •  Lethargy,  anorexia,  vomiting,  diarrhea,   •  Serum biochemistry profile: increased alkaline
                                                polyuria/polydipsia, discolored urine, weight   phosphatase, alanine aminotransferase, bili-
           Definition                           loss                                rubin concentrations. Hemolysis of sample
           Twisting  and  rotation  of  the  spleen  around                         often noted
           its vascular pedicle, resulting in occlusion and   PHYSICAL EXAM FINDINGS  •  Coagulation profile
           thrombosis of vasculature and splenic conges-  •  Abdominal distention  •  Urinalysis: hemoglobinuria common
           tion and ischemia                   •  Mid-abdominal mass/splenomegaly  •  Abdominal radiographs: splenomegaly
                                               •  Signs  of  hypotensive  shock  if  acute  form   ○   Spleen may have a reversed C shape.
           Epidemiology                         (tachycardia, pallor, prolonged capillary refill   ○   Gas  opacities  in  spleen  in  chronic
           SPECIES, AGE, SEX                    time, weak peripheral pulse)          torsions
           Dogs:                                                                    ○   Loss of abdominal detail consistent with
           •  Deep-chested large and giant breeds (Great   Etiology and Pathophysiology  effusion
             Dane, Saint Bernard, German shepherd, Irish   •  Twisting  of  vasculature  results  in  venous   ○   Displacement of small intestine
             setter)                            occlusion first. The arterial system remains   •  Abdominal ultrasound
           •  No age predisposition             patent, resulting in a large and painful spleen.  ○   Generalized splenomegaly
           •  Males more commonly affected     •  Proposed mechanism                ○   Lacy, diffusely hypoechoic splenic
                                                ○   Gastric  distention  repeatedly  stretches   parenchyma
           RISK FACTORS                           gastrosplenic and splenocolic ligaments,   ○   Thrombi located within splenic vasculature
           Spontaneously resolving gastric dilation and   allowing splenic hypermotility.  ○   Color-flow Doppler: decreased blood flow
           volvulus (GDV) can occur in conjunction with   ○   Spontaneous resolution of GDV may leave   to the hilar vessels
           splenic torsion                        the spleen in a rotated position.  •  Electrocardiogram   (ECG):   ventricular
                                               •  Intravascular microangiopathic hemolysis is   arrhythmias are common.
           ASSOCIATED DISORDERS                 a common complication.
           •  GDV (can occur following splenectomy for                            Advanced or Confirmatory Testing
             splenic torsion)                   DIAGNOSIS                         CT:  corkscrew-like  soft-tissue  mass  in  the
           •  Splenic infarction                                                  location of the splenic artery and vein
                                               Diagnostic Overview
           Clinical Presentation               Diagnosis  is  suspected  based  on  patient  sig-
           DISEASE FORMS/SUBTYPES              nalment, history, and physical exam findings.    TREATMENT
           •  Acute                            Abdominal diagnostic imaging (radiography,   Treatment Overview
           •  Chronic                          ultrasound) demonstrates the uniformly   Splenectomy is the required treatment and
                                               enlarged, malpositioned spleen.    should be performed as soon as the patient is
           HISTORY, CHIEF COMPLAINT                                               stable. Intensive postoperative care is necessary.
           Acute:                              Differential Diagnosis
           •  Collapse                         •  Splenic mass                    Acute General Treatment
           •  ± GDV and associated signs       •  Neoplasia of other abdominal organs  Preoperative patient stabilization
           •  Signs of hypovolemic or toxic shock  •  GDV                         •  Correct fluid and electrolyte imbalances.
           Chronic:                            •  Mesenteric volvulus             •  Blood transfusion: if hematocrit < 20% (p.
           •  Vague,  nonspecific  history:  difficult  to                          1169)
             distinguish from other disorders that cause   Initial Database       •  Treat cardiac arrhythmias (pp. 1033 and 1457)
             signs of abdominal pain           •  CBC: anemia, leukocytosis (stress leukogram   •  Preoperative  and  perioperative  broad-
           •  Signs may be present for up to 3 weeks.  common)                      spectrum antibiotics


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