Page 1886 - Cote clinical veterinary advisor dogs and cats 4th

945.e4 Storage Diseases

euthanasia or death within 1-2 years of (e.g., urine scald, decubital ulcers, aspiration ADDITIONAL SUGGESTED
diagnosis. pneumonia) and provide the animal with the READINGS
VetBooks.ir PEARLS & CONSIDERATIONS progresses. Bradbury AM, et al: A review of gene therapy in
best possible quality of life as the disorder
canine and feline models of lysosomal storage
disorders. Hum Gene Ther Clin Dev 26:27-37,
Client Education
Comments
2015.
• The field of medical genetics is rapidly • Caution owners about the possibility of Dewey CW: Encephalopathies: disorders of the brain.
advancing, and genetic tests and therapies personality changes or aggressive behavior In Dewey CW, et al, editors: A practical guide to
such as gene transfer therapy may provide associated with these disorders, especially in canine and feline neurology, ed 3, Ames, IA, 2015,
a more favorable prognosis in the future. animals that have contact with children. Wiley-Blackwell, pp 141-236.
• Consultation with a veterinary neurologist • Counsel owners concerning the progressive Skelly BJ, et al: Recognition and diagnosis of
is recommended to obtain the most up-to- nature of storage disorders and likelihood lysosomal storage diseases in the cat and dog. J
Vet Intern Med 16:133-141, 2002.
date diagnostic and treatment information of eventual euthanasia. Vite CH, et al: Effective gene therapy for an inherited
available. • Counsel breeders about the inheritance CNS disease in a large animal model. Ann Neurol
of the condition and availability of DNA 57:355-364, 2005.
Prevention testing.
• Maintain responsible breeding practices. Reproduced from the second edition in modi-
• Genetic testing is available for a limited SUGGESTED READING fied form.
number of these storage diseases and can Coates JR, et al: Inherited peripheral neuropathies SECOND EDITION AUTHOR: Lauren R. Talarico, DVM,
be used to identify carriers. in dogs and cats. Vet Clin North Am Small Anim DACVIM
Pract 34:1361-1401, 2004. EDITOR: Karen R. Muñana, DVM, MS, DACVIM
Technician Tips
Proper nursing care is important to minimize
potential complications of neurologic disease

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