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Wolff-Parkinson-White Syndrome 1049.e3


           •  Thoracic radiographs             •  Antiarrhythmic  drug  therapy  is  used  to   •  May  require  Holter  monitoring  (rarely,
                                                                                    multiple Holters) for documentation
             ○   Assess cardiac silhouette (normal to   control tachyarrhythmias if the owner is   •  Even dogs with tachycardiomyopathy and
  VetBooks.ir  ○   Assess pulmonary vasculature and lung   •  Pimobendan,  neurohormonal  modulators,   CHF can be cured with successful ablation   Diseases and   Disorders
                                                unable to proceed with catheter ablation.
               severely enlarged).
                                                and diuretics for tachycardia-induced
               fields (for congestion and edema).
                                                                                    of the AP.
           •  Physical tests
             ○   Vagal maneuver may terminate a tachyar-  cardiomyopathy          Technician Tips
               rhythmia by inducing transient AV nodal   Behavior/Exercise        Teaching the owner to count the heart rate at
               blockade but generally is unsuccessful.  Restricted exercise is recommended until   home for regular monitoring is very important
                                               antiarrhythmic  control  and  control  of  CHF   in these cases, particularly for those in which
           Advanced or Confirmatory Testing    signs are achieved.                medical management is chosen rather than the
           •  Holter  monitoring  can  be  helpful  in                            ablation procedure.
             capturing intermittent pre-excitation or   Drug Interactions
             tachyarrhythmias.                 •  Potential interactions between digoxin and   Client Education
           •  Drug  administration:  IV  lidocaine  is  suc-  several antiarrhythmic and commonly used   •  Monitor heart rate carefully at home.
             cessful in blocking many but not all APs   drugs.                    •  Sustained  tachyarrhythmias  are  life-
             and rarely terminates other narrow complex   •  Beta-agonists  or  other  stimulants  are   threatening.
             tachyarrhythmias. It can serve as a diagnostic   contraindicated.    •  Curative procedures are available.
             and therapeutic test. IV diltiazem can
             terminate AV reciprocating tachycardia by   Possible Complications   SUGGESTED READING
             inducing AV nodal block, but it also can   •  Tachycardia-induced cardiomyopathy  Wright KN, et al: Atrioventricular accessory pathways
             terminate certain other tachyarrhythmias.   •  CHF                    in  89  dogs:  clinical  features  and  outcome  after
             Blood pressure (BP) monitoring and resus-  •  Sudden death            radiofrequency catheter ablation. J Vet Intern Med
             citation equipment should be available.  •  Side effects of antiarrhythmic drugs  32:1517-1529, 2018.
           •  Electrophysiologic   testing   definitively
             establishes the presence or absence of an   Recommended Monitoring   ADDITIONAL SUGGESTED
             AP and its location along the AV groove.   •  Follow-up exam, ECG, and Holter monitor-  READINGS
             Radiofrequency  catheter  ablation  can  be   ing: frequency depends on the severity of the   Santilli RA, et al: Anatomic distribution and elec-
             curative during the same study.    tachyarrhythmias documented.       trophysiologic properties of accessory pathways in
                                               •  Radiographic and echocardiographic moni-  dogs. J Am Vet Med Assoc 231:393-398, 2007.
           TREATMENT                            toring for dogs with tachycardia-induced   Santilli RA, et al: Radiofrequency catheter ablation of
                                                cardiomyopathy: with adequate control of   accessory pathways in the dog: the Italian experi-
           Treatment Overview                   tachyarrhythmias (particularly with a curative   ence. J Vet Cardiol 20:384-397, 2018.
           Goals of treatment are to terminate any tachyar-  ablation procedure), myocardial function   Wright KN: Assessment and treatment of supraven-
                                                                                   tricular tachyarrhythmias. In Bonagura JD, editor:
           rhythmia present, control its recurrence, and   and chamber dilation should significantly   Kirk’s Current veterinary therapy XIII, Philadelphia,
           control signs of congestive heart failure (CHF)   improve within 3 months.  2000, Saunders, pp 726-730.
           and hypotension.                                                       Wright KN: Interventional catheterization for tachyar-
                                               PROGNOSIS & OUTCOME                 rhythmias. Vet Clin North Am Small Anim Pract
           Acute General Treatment                                                 34:1171-1185, 2004.
           •  Incessant narrow complex tachyarrhythmias:   •  Excellent  with  radiofrequency  catheter
             aimed at slowing AV nodal conduction or   ablation                   RELATED CLIENT EDUCATION
             blocking the AP: lidocaine 2-8 mg/kg total   •  Fair  long  term  with  antiarrhythmic  drug   SHEETS
             dose IV or diltiazem 0.125-0.35 mg/kg, slow   administration
             IV (in 2 mg/kg boluses) over 4-5 minutes is   •  Poor if tachyarrhythmias are not controlled: pro-  Consent to Perform Echocardiography
             most commonly used. Procainamide 6-8 mg/  gressive cardiomyopathic changes (eventually    Heart Failure
             kg slow IV over 5 minutes or amiodarone   not completely reversible) and recurrent CHF
             (without preservatives or Nexterone to reduce   result. Sudden death becomes more common.  AUTHOR: Kathy Wright, DVM, DACVIM
             risk of side effects) 3-5 mg/kg slow IV over                         EDITOR: Meg M. Sleeper, VMD, DACVIM
             10-15  minutes  can  also  be  successful  in   PEARLS & CONSIDERATIONS
             terminating OAVRT.
           •  Synchronized  direct  current  (DC)  cardio-  Comments
             version can be used after the patient is   •  WPW is an important differential diagnosis
             anesthetized or unconscious if drugs are   in a young (<6  years  old)  dog  presenting
             unsuccessful.                      with DCM-like signs.
           Chronic Treatment
           •  Radiofrequency catheter ablation of the AP
             is a curative procedure.













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