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1100.e2  Epidural Analgesia/Anesthesia




            Epidural Analgesia/Anesthesia                                                          Client Education
                                                                                                         Sheet
  VetBooks.ir                                                                    Preparation: Important

                                              •  Use  of  potent  parenteral  or  systemic
           Difficulty level: ♦♦
                                                vasodilators                     Checkpoints
           Synonym                                                               •  Base dosages on lean body weight.
           Extradural blockade                Equipment, Anesthesia              •  Consider ratio of each component: opioid,
                                              Most  animals  that  receive  an  epidural  are   local anesthetic, alpha-agent, ketamine, and/
           Overview and Goals                 heavily sedated or under general anesthesia   or others; total volume should not exceed
           Administration of drugs into the epidural space   at the time of administration. Premedication   0.2 mL/kg.
           to provide decreased sensory and sympathetic   with both anxiolytic and analgesic drugs   •  Positioning of animal: sternal recumbency,
           pain transmission, modulation (analgesia), and/  (opioid, alpha-agonist) is recommended even   with  hindlimbs  pulled  fully  cranially
           or complete motor blockade (anesthesia). Drugs   if continued progression into general anesthesia   under body or else flexed and stable under
           can be administered in a single dose, repetitively,   is not anticipated because of the pain of   pelvis (frog-legged position). Because aged,
           or by continuous infusion by catheter:  positioning, approach, and administration of     debilitated, or traumatized animals may be
           •  Epidural analgesia: injection of an opioid,   epidural agents.       uncomfortable in either position, lateral
            a phencyclidine, an alpha-agonist, or a   Equipment:                   positioning is also used. Obese animals are
            nonsteroidal antiinflammatory drug  •  Hair clippers                   best placed in sternal recumbency because of
           •  Epidural  anesthesia: injection of a local   •  Surgical scrub solution, isopropyl alcohol or   ease in identifying LS space and for optimal
            anesthetic                          saline, gauze/sponge               oxygenation and ventilation.
                                              •  Epidural or spinal needle (Quincke, Hustead,   •  Premedication for surgery, general anesthesia,
           Indications                          or Tuohy needles) 22 to 20 gauge;  1 - to   or procedural sedation suggested below
                                                                          2
           Cesarean section; thoracotomy; pelvic, hindlimb,   3 2 -inch,  small hypodermic  needles  (22   ○   Dexmedetomidine 3-10 mcg/kg canine,
                                                 1
           perineal,  or  tail  orthopedic  manipulations;   gauge) can also be used for smaller patients.  1-3 mcg/kg feline IM or IV, with
           amputations (forelimb/hindlimb); abdominal   •  Sterile gloves          ○   Midazolam 0.2-0.5 mg/kg IM or IV
           procedures; diaphragmatic repair; pancreatitis;   •  Sterile saline for dilution of agents  and either butorphanol 0.2 mg/kg or
           peritonitis; intervertebral disc disease (IVDD);   •  “Test syringe” for saline and air mix  hydromorphone 0.1 mg/kg IM or IV
           management of chronic pain (e.g., lumbosa-  •  Syringe for administration of combination
           cral  [LS]  disc  disease,  spinal  or  nerve  root     of local and/or opioid  Possible Complications and
           tumor)                             •  A few 20-gauge needles (used for withdraw-  Common Errors to Avoid
           Advantages:                          ing drugs from vials)            •  The  following  can  be  seen  with  technical
           •  Lengthy, rapid-onset analgesia  •  Local  anesthetics  for  epidural  injection:   difficulty in identifying (finding) the epidural
           •  Few  systemic  side  effects  due  to  limited   0.5% bupivacaine, 2% lidocaine, or 0.75%   space: infection, hemorrhage, spinal or nerve
            vascular uptake of substances       ropivacaine (preferentially preservative free,   root trauma.
           •  Reduced  requirements  for  parenteral  and   must be epinephrine free)  •  The following can be seen with use of certain
            inhalant analgesic/anesthetic drugs  •  Opioids for epidural injection: morphine,   agents: respiratory depression, urinary retention,
           •  Alternative to general anesthesia for animals   preferably preservative free (Duramorph,   pruritus, nausea and vomiting (opioids), motor
            at high risk                        Astramorph, preservative-free morphine);   paralysis, systemic vasodilation (lidocaine or
                                                buprenorphine, oxymorphone, hydromor-  high doses of bupivacaine/ropivacaine).
           Contraindications                    phone, dexmedetomidine, and ketamine may   •  Subarachnoid injection frequently results in
           Absolute contraindications:          also be used.                      superb analgesia but can cause respiratory
           •  Coagulopathy/bleeding disorder  •  A second operator (assistant) to allow strict   depression.
           •  Localized infection/inflammation over entry   attention to aseptic technique
            to epidural space                 For epidural catheterization, the following also   Procedure
           •  Increased  intracranial/intraspinal  pressure   are required:      •  Find the entry site: The LS space is routinely
            (head trauma, space-occupying mass)  •  Blunt-tipped, lateral-faced opening needle   used for accessing the epidural space. It is
           •  Risk  of  or  existing  severe  respiratory   with curved bevel (Tuohy needle)  identified by palpating the most craniodorsal
            depression (phrenic nerve injury, tentorial   •  Continuous or indwelling epidural catheter  aspects of each ilial wing, drawing an imagi-
            herniation)                       •  Injection port with screw or lock fitting to   nary line between wings, and palpating the
           Relative contraindications (requires alteration   avoid inadvertent disconnection  spinous process of L7 caudal to this line.
           of dose, frequency, drugs, or placement site):  •  Sterile scissors to tailor-cut the catheter to   The  spinous  process  of  L7  is  smaller  and
           •  Urinary retention                 proper length                      shorter than that of L6 and therefore is
           •  Meningitis, encephalitis, discospondylitis  •  Microfilter           often more difficult to find, but it is always
           •  Severe anatomic/neurologic disturbance or   •  Sterile  covering  for  site  and/or  part/total   CAUDAL  to  this  imaginary  line.  Staying
            obesity at landmarks                catheter (Tegaderm)                directly  on  midline,  the  site  of  entry  (LS
           •  Inexperienced administration    •  Suture material (3-0 nylon or other monofila-  space) is identified by placing a fingertip on
           Contraindications for use of local anesthetics   ment, nonabsorbable suture)  the spinous process of L7 and gently rocking
           in epidurals:                      •  Needle holders                    the finger caudally into the depression caudal
           •  Uncorrected   hypovolemia   or   active   •  Suture scissors         to the process. The needle entry site is in
            hemorrhage                                                             this depression.
           •  Vasodilatory shock              Anticipated Time                   •  The animal is positioned appropriately, the
           •  Severe clinical cardiac disease or liver impair-  •  Experienced operator: 3-5 minutes  approximate LS area clipped, and then asepti-
            ment (third-space fluid disease, ascites)  •  Inexperienced  operator,  anatomic/animal   cally prepped three times using alternating
           •  Acute kidney injury               positioning issues, dermatologic uncleanli-  chlorhexidine scrub and saline.
           •  Sympathetic  disturbance  (e.g.,  autonomic   ness: 20 minutes; if it takes longer, consider   •  Sterile gloves are unwrapped, and the paper
            disease, dysautonomia)              alternative forms of analgesia instead  sleeve  is used  as  a sterile  field;  syringes,

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