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Lithotripsy 1127.e3



                                                                                                          Video
            Lithotripsy                                                                                 Available
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                                               •  Rare: urethral or bladder perforation (due
           Difficulty level: ♦♦♦
                                                to laser contact with the mucosa or to
           Synonyms                             voiding urohydropulsion [VUH]), urethral
           Electrohydraulic lithotripsy (EHL), laser litho-  obstruction, indwelling urinary catheter for
           tripsy (holmium-doped yttrium, aluminum,   1-5 days after the procedure, urinary tract
           garnet [Ho:YAG] laser)               infection
                                               •  Endoscope damage: probe activated within
           Overview and Goal                    the endoscope
           Fragmentation and removal of uroliths through   •  Precautions
           natural orifices                     ○   Avoid activating laser against the mucosa
                                                  or closer than 1 mm, flush abundantly                               Procedures and   Techniques
           Indications                            while checking the bladder, and use rigid
           Treatment of bladder and urethral uroliths in   cystoscope in females whenever possible.
           dogs and female cats                 ○   VUH the day after lithotripsy if remaining
                                                  fragments
           Contraindications                    ○   Selection of candidates depends on sex,   LITHOTRIPSY  Endoscopic image demonstrates
                                                                                  two uroliths in the bladder of a dog. The probe is
           Untreated bleeding diathesis           size/shape/location of uroliths  seen emerging from the bottom of the image and
                                                  ■   Male dogs with urethral stones or two   contacting the urolith on the right in preparation for
           Equipment, Anesthesia                    or three bladder  stones  <  5-6 mm   fragmentation.
           •  General anesthesia                    (stones can be brought into the urethra
           •  Epidural  anesthesia  can  facilitate  voiding   for fragmentation,  which facilitates
             urohydropulsion by relaxing the urethra.  fragment expulsion)        •  Stone analysis
           •  Endoscope: flexible ureteroscope (males and   ■   Female dogs with urethral stones or   •  Five  days  (or  longer  if  positive  urine
             small females), rigid cystoscope (females or   one to five bladder stones < 1 cm  culture) of broad-spectrum antibiotic (e.g.,
             perineal access in male dogs)        ■   Female cats with urethral stones or one   amoxicillin)
           •  Sterile saline and 60-mL syringes     to five bladder stones < 5-6 mm  •  Repeat lithotripsy and/or VUH to remove all
           •  Protective eyewear                                                    fragments (nidus for new uroliths) if needed.
           •  Ho:YAG laser or EHL probe        Procedure
           •  Stone retrieval basket           •  Performing lithotripsy requires at least two   Alternatives and Their
                                                people (clinician and assistant).  Relative Merits
           Anticipated Time                    •  Patients are placed under general anesthesia.   •  Lithotripsy is an excellent, minimally inva-
           Varies (mean, 30 minutes). Depends on urolith   Females are positioned in dorsal recumbency   sive alternative to urethrotomy for urethral
           location (longer in bladder than in urethra); sex   and males in lateral recumbency (exception:   stones.
           of the patient (longer in males than in females);   dorsal recumbency for perineal approach in   •  Cystotomy,  a  more  invasive  procedure,
           number, size, and shape of the urolith (longer   males). The vulva or prepuce is aseptically pre-  allows the removal of bladder uroliths and
           for multiple and/or large uroliths); visibility in   pared. The cystoscope/ureteroscope is passed   retropulsed urethroliths. Sutures can serve
           the bladder (longer if hematuria)    through the urethra. Saline is injected through   as nidus for new stone formation.
                                                the endoscope to distend the bladder and   •  A  percutaneous  cystolithotomy  (PCCL)
           Preparation: Important               localize the urolith(s). In male dogs, perineal   approach to bladder urolith removal can be
           Checkpoints                          access can be used to pass the cystoscope.  used in small patients when the endoscope is
           •  Urine culture and sensitivity 5 days before   •  The  probe  is  passed  through  the  working   too large to pass through the urethra (male
             the procedure and appropriate antibiotic   channel of the scope until it contacts the   dogs ≤ 5 kg, male cats) or there are multiple
             therapy if needed                  urolith and is activated, applying laser energy   or very large uroliths (cats and dogs).
           •  Coagulation  profile  (notably  for  dogs    directly to the urolith (see Video). As soon as   •  Extracorporeal  shock  wave  lithotripsy
             of breeds  predisposed  to  von  Willebrand    the urolith is fragmented (small enough to   (ESWL) consists of fragmenting uroliths
             disease)                           pass through the urethra), basket removal can   by delivering external shock waves through
           •  Protective eyewear                be attempted to remove the big fragments,   a water bath or a specific fluid-filled cushion.
           •  Gauze squares over the eyes of the patient   and VUH (saline) is performed to remove   It has been very successful in fragmenting
             (if using laser)                   the remaining smaller fragments from the   nephroliths and ureteroliths in dogs but less
           •  Lateral  abdominal  radiograph  before  the   urinary tract.          successful for cystoliths and urethroliths.
             procedure to check if stones are still present   •  The  endoscope  can  then  be  reintroduced
             and to measure and count them      to check for remaining fragments, and   Pearls
                                                if needed, a new series of fragmentation,   •  Lithotripsy’s  success  depends  on  careful
           Possible Complications and           basket removal, and VUH can be performed.   patient selection (sex, size of the patient,
           Common Errors to Avoid               Urolith fragments should be sent for culture   number/size of uroliths,  and presence of
           •  Most complications occur during or within   and mineral analysis.     hematuria)
             24 hours of the procedure.                                           •  Basket removal or VUH allows removal of
           •  In  dogs,  minor  complications  related  to   Postprocedure          remaining fragments.
             cystoscopic-guided  laser lithotripsy are   •  Analgesia (preferably opioids or nonsteroidal
             reported in 13% (male) to 18% (female)   antiinflammatory drugs [NSAIDs] if no renal   SUGGESTED READING
             of cases.                          compromise and well hydrated)     Adams LG, et al: Use of laser lithotripsy for fragmen-
           •  Common:  hematuria,  stranguria  usually   •  Radiographs or ultrasound to check for the   tation of uroliths in dogs: 73 cases (2005-2006). J
             self-limiting within 48 hours      presence of uroliths/fragments     Am Vet Med Assoc 232:1680-1682, 2008.

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