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114   Bee and Other Insect Stings


            not certain the pathogen can be eliminated   •  Veterinarians  and  veterinary  technicians   SUGGESTED READING
            by treatment,  and 2) even if the cat is   are at a higher risk than the general popu-  Breitschwerdt EB: Bartonellosis, one health and all
  VetBooks.ir  Prevention                       that have fleas should be treated for     AUTHOR: Leah A. Cohn, DVM, PhD, DACVIM
                                                lation for Bartonella spp infection. Animals
            bacteremic, zoonosis is not transmitted to
                                                                                   creatures great and small. Vet Dermatol 28:96-e21,
            people in the absence of fleas.
                                                                                   2017.
                                                fleas (e.g., nitenpyram) before hospitaliza-
                                                tion.
           Strict prevention of ectoparasites (fleas, ticks);   •  Needlestick transmission of B. henselae and   EDITOR: Joseph Taboada, DVM, DACVIM
           avoid allowing animals to roam       B. vinsonii subsp berkhoffii have been docu-
                                                mented in veterinary workers.
           Technician Tips
           •  People  diagnosed  with  cat-scratch  disease   Client Education
            need not get rid of the cat. Instead, strict   Strict flea control is the best way to avoid
            flea control is warranted.        zoonotic infection with Bartonella spp.




            Bee and Other Insect Stings



            BASIC INFORMATION                     often show signs of pruritus, dyspnea,   •  Blood glucose
                                                  salivation, incoordination, and collapse.  •  Blood urea nitrogen/creatinine
           Definition                           ○   Animals with massive envenomation may
           Stings from insects such as bees, wasps, and   show signs of acute respiratory distress   Advanced or Confirmatory Testing
           hornets. Spider envenomation is discussed   syndrome (p. 27) or disseminated intra-  Rarely required except in cases of anaphylaxis
           separately (p. 928).                   vascular coagulation (p. 1218).  (p. 54)
           Epidemiology                       Etiology and Pathophysiology
           SPECIES, AGE, SEX                  •  Most systemic signs result from an immu-   TREATMENT
           More likely to occur in young, inquisitive   noglobulin E (IgE)–mediated allergic reaction   Treatment Overview
           animals. Cats may be more tolerant than dogs   (p. 1238).             Provide relief of discomfort, address hypersen-
           to many insect toxins.             •  Bee stings result in the loss of the stinger,   sitivity reaction
                                                which remains in the victim, and the venom
           GENETICS, BREED PREDISPOSITION       sac (if attached) will continue to administer   Acute General Treatment
           Boxers and pit bulls seem especially prone to   venom (apitoxin).     Facial edema/urticaria:
           insect hypersensitivity.             ○   Melittin is a major component of apitoxin,   •  Remove stinger if present. Use fine forceps/
                                                  and with phospholipase A 2 , it results in   tweezers or a flat object (e.g., dull side of a
           GEOGRAPHY AND SEASONALITY              altered cell permeability, prostaglandin   scalpel blade), taking care not to press on
           Bee stings are more common during warm   production, and cell death. Other com-  the stinger’s sac (if present).
           weather when insects are active.       ponents include histamine and hyaluroni-  •  Diphenhydramine 1-2 mg/kg IM
                                                  dase, which support inflammation and   •  Dexamethasone sodium phosphate 0.2 mg/
           Clinical Presentation                  tissue damage.                   kg IM or slow IV
           HISTORY, CHIEF COMPLAINT           •  Wasps can sting multiple times and inject   Anaphylaxis may require diphenhydramine and
           For bees, wasps, hornets (order Hymenop-  a small amount of venom at each sting.  dexamethasone, as well as one or more of the
           tera), usually, sting is unwitnessed. Instead,   ○   Venom contains histamine, hyaluronidase,   following treatments, according to escalating
           animals present for clinical signs associated   phospholipase, and other small peptides.   degree of severity of the reaction:
           with allergic reaction (p. 54). Severity of signs   The  venom  also  contains  acetylcholine,   •  Intravenous isotonic crystalloid fluids (up to
           will depend on the type of venom, location of   which contributes to pain.  45-90 mL/kg IV, given incrementally)
           the sting, number of stings, and sensitivity of   •  A small number of dogs and cats may develop   •  Epinephrine 0.01 mg/kg IV
           the animal receiving the sting.      anaphylaxis.
                                                                                 Behavior/Exercise
           PHYSICAL EXAM FINDINGS              DIAGNOSIS                         Animals should be leash-walked or supervised
           •  Bees, wasps, hornets                                               when outside to avoid re-exposure.
            ○   Local reaction associated with an immu-  Diagnostic Overview
              nologic response is the most common   The diagnosis is frequently presumptive and based   Recommended Monitoring
              finding.  This  may  include  a  swollen   on clinical signs and history of possible exposure.   Animals with facial swelling or urticaria should
              head/face or diffuse urticaria. Cases   Stings are seldom witnessed by pet owners.  be monitored for 20-30 minutes to ensure
              with severe facial swelling can develop                            clinical signs are not progressing.
              upper airway obstruction and respiratory    Differential Diagnosis
              distress.                       •  Cellulitis                       PROGNOSIS & OUTCOME
            ○   Less commonly, an animal may develop   •  Peripheral edema
              anaphylaxis,  usually  within  15  minutes   •  Other causes of allergy or anaphylaxis  Most animals with insect bites and stings
              of sting (p. 54). Anaphylaxis in dogs                              have an excellent prognosis. Animals with
              manifests as vomiting, defecation,   Initial Database              severe systemic signs have a more guarded
              urination, muscular weakness, collapse,   •  Packed cell volume    short-term prognosis as dictated by the severity
              respiratory depression, or seizures. Cats   •  Serum total protein  of signs.

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