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Petechiae and Ecchymoses 1439.e3

Petechiae and Ecchymoses
VetBooks.ir

Petechiae
and ecchymoses
Review history for
incriminating
Platelet count or estimate medications
<30,000/mcL or <3/HPF >30,000/mcL

Complete blood count Buccal mucosal bleeding time
Normal Normal Prolonged

Thrombocytopenia Thrombocytopenia • Problem resolved Insufficiently
only and anemia • Local disease sensitive assay
• Vasculitis
Infectious disease
testing, as (+) Specific Reticulocyte von Willebrand
appropriate treatment count factor assay
(e.g., anaplasmosis,
ehrlichiosis) Low Normal
(–)
60,000/mcL 60,000/mcL 60,000/mcL von Willebrand PFA-100
with blood loss with hemolysis disease Platelet
aggregation
Coagulation • Blood smear for spherocytes, Abnormal Normal
screen
(e.g., PT, aPTT) parasites, autoagglutination
• Coombs’ test Thrombopathy Vascular
Normal Abnormal • Antinuclear antibody titer disorder
• Heartworm serologic test
• Infectious disease serologic titer/
Immune-mediated Consumptive polymerase chain reaction (PCR)
thrombocytopenia coagulopathy Special platelet Skin biopsy
Positive Negative studies

• Evans syndrome Continue search for
Search for • Systemic lupus underlying disease
underlying disease erythematosus Search for
• Vaccine • Heartworm disease hereditary or
• Drug • Infectious disease acquired underlying
• Cancer disease
• Infection

• Bone marrow examination
• Splenic aspirate and cytologic evaluation Clinical Algorithms
• Infectious disease serologic titer/
polymerase chain reaction test
• Thoracic and abdominal radiographs
• Toxicologic and drug studies
• Estrogen level (dog)
• Feline leukemia virus
• Feline immunodeficiency virus
Negative Abnormal

Immune-mediated Thrombocytopenia associated
thrombocytopenia with underlying disease

HPF, High-power field.
NOTE: The unit of measure of micron, sometimes denoted by the Greek letter µ, is abbreviated in this text by mc. For example,
1 mcL = 1 microliter; 1 mcg = 1 microgram.
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