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1444  Protein-Losing Nephropathy



            Protein-Losing Nephropathy
  VetBooks.ir                                             Proteinuria




                                                               Recheck in 2 weeks

                                                 Transient           Persistent

                                            •  Consider resolved or  Urine sediment
                                               intermittent disease
                                            •  Re-evaluate



                                                       Negative                     Positive

                                                        Urine                 Consider postglomerular
                                                  protein/creatinine ratio         proteinuria


                                              >0.5 (dog)             <0.5 (dog)
                                              >0.4 (cat)             <0.4 (cat)


                                             Serum albumin          Re-evaluate
                                                                   in 3–6 months

                              Normal/increased            Normal/decreased


                                                         Consider glomerular
                            Consider preglomerular           proteinuria
                                 proteinuria
                                                        Search for risk factors,
                                                          underlying disease


                                                          Renal biopsy ideal


                                               Glomerulonephritis   Renal amyloidosis

                                            Hereditary nephropathy  Glomerulosclerosis

                                          Membranous nephropathy   Minimal change disease

           UPDATED AND EDITED BY: Leah A. Cohn, DVM, PhD, DACVIM
           ORIGINALLY WRITTEN BY: Anne M. Dalby, DVM, DACVIM


















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