Page 365 - Cote clinical veterinary advisor dogs and cats 4th

Chemotherapy: Adverse Events 153.e1

VetBooks.ir Diseases and Disorders

CHEMOTHERAPY: ADVERSE EVENTS Soft-tissue injury caused by extravasation of doxorubicin approximately
2.5 weeks prior. Doxorubicin was administered with an infusion pump. Extravasation was noted. No treatment
for extravasation was administered. The injury progressed proximally from the catheter site to the dog’s axilla
and ventral thorax. The dog was euthanized.

CHEMOTHERAPY: ADVERSE EVENTS Soft-
tissue injury caused by extravasation of vincristine
14 days prior. Extravasation was not noticed at the
time of treatment. The dog licked the site, resulting in
a secondary infection. The injury resolved in 1 month
with cephalexin, wound management, and an e-collar.

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