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Dehydration   243


           •  Closely monitor the patient for urine scald   •  Sling support or a cart can assist with patient   SUGGESTED READING
             and decubitus ulceration when the disease   •  Physical rehabilitation using range-of-motion   Coates JR, et al: Canine degenerative myelopathy.
                                                mobility.
             progresses to LMN involvement.
  VetBooks.ir  Client Education                 and isometric exercises will help maintain   AUTHOR: Joan R. Coates, DVM, MS, DACVIM  Diseases and   Disorders
                                                                                   Vet Clin North Am Small Anim 40:929-950, 2010.
                                                joint flexibility and muscle strength.
                                                                                  EDITOR: Karen R. Muñana, DVM, MS, DACVIM
           •  Meticulous nursing care is essential for the
             recumbent patient.                •  It is important to realize the emotional support
                                                an individual or family can provide to main-
             ○   Keep patient clean and dry to prevent   tain quality of life for a companion animal.
               urine scald.                     As a DM-affected dog progresses through the
             ○   Keep patient  on a  protective surface   disease stages, the dog’s owner encounters
               (optimize padding, traction, and ease of   the challenges of at-home management and
               cleaning).                       providing appropriate daily care for the pet.



            Dehydration                                                                            Client Education
                                                                                                          Sheet


            BASIC INFORMATION                  HISTORY, CHIEF COMPLAINT           •  Tacky  mucous  membranes:  oral  mucous
                                               Anorexia, vomiting, diarrhea, lethargy, weakness,   membranes may be tacky due to panting;
           Definition                          panting, and signs related to underlying disease  nausea with hypersalivation or recent water
           Clinical  state  in  which  fluid  losses  (sensible                     consumption can obscure recognition of
           loss [renal] and insensible loss [normal daily   PHYSICAL EXAM FINDINGS  tacky membranes.
           gastrointestinal, respiratory]) exceed fluid intake  •  Lethargy,  dry/tacky  mucous  membranes,
                                                tachycardia, poor pulse quality, skin tenting,   Initial Database
           Synonyms                             sunken eyes/enophthalmos, and weight loss.  •  CBC, serum biochemical profile, urinalysis,
           Decreased circulating blood volume, negative   •  The  approximate  level  of  dehydration  is   fecal exam, ± imaging studies to look for
           fluid balance                        estimated based on the following physical   cause
                                                exam  findings: 5%  = dry/tacky mucous   •  Depending  on  degree  and  on  comorbid
           Epidemiology                         membranes; 6%-8% = dry mucous mem-  disease, dehydration can cause increased
           SPECIES, AGE, SEX                    branes and delayed skin tent test; 10%-12%   packed cell volume (PCV), increased total
           All animals are  susceptible to  dehydration,   = hypovolemic shock      solids, increased albumin, increased blood
           depending on the underlying disease process.   ○   Signs of shock include all of the above   urea nitrogen (BUN) ± creatinine, increased
           Due to a high ratio of body surface area to   plus bilaterally symmetrical enophthalmos,   sodium, concentrated urine (>1.040  dog;
           volume, smaller animals (<10 kg)  are  more   tachycardia (dogs), weakness, slow capil-  > 1.050 cat).
           prone to dehydration.                  lary refill time, poor pulse, and lethargy
                                                  or obtundation.                 Advanced or Confirmatory Testing
           RISK FACTORS                                                           Diagnostics are dictated by initial diagnostic
           •  Diseases  and  toxins  that  affect  appetite,   Etiology and Pathophysiology  information and case evolution.
             decrease  water  consumption,  and  hamper   •  Causes: see Risk Factors above
             renal and intestinal conservation of water;   •  Mechanism: regardless of cause, dehydration    TREATMENT
             poor vascular integrity            results in a decrease in circulating blood
           •  Infectious diseases (e.g., parvoviral enteritis,   volume, which directly affects perfusion and   Treatment Overview
             coccidiosis); metabolic disturbances sec-  oxygen delivery to essential tissues/organs.   •  Fluid replacement
             ondary to chronic kidney disease, hypo-  Mild cases may be clinically insignificant,   •  Correction of electrolyte abnormalities
             adrenocorticism, gastrointestinal disease,   but in moderate or severe dehydration, the   •  Treatment of underlying disease
             and other disorders with systemic effects;   metabolic processes in hypoperfused tissues
             endocrinopathies  (e.g., diabetes mellitus,   must rely on anaerobic pathways to produce   Acute General Treatment
             diabetes insipidus); and intoxications (e.g.,   adenosine triphosphate, which is a less   Fluid replacement with an isotonic crystalloid
             ethylene glycol)                   efficient process. A byproduct of anaerobic   such as lactated Ringer’s solution, Normosol-R,
                                                metabolic  pathways  is lactic  acid, which   or 0.9% sodium chloride
           CONTAGION AND ZOONOSIS               accumulates in states of decreased perfusion   •  Maintenance rate and dehydration replace-
           Some of the diseases that cause dehydration   and results in metabolic acidosis.  ment must be calculated.
           (e.g., parvoviral enteritis, leptospirosis) are                        •  Dehydration  volume  is  delivered  over
           contagious to other pets and/or have zoonotic    DIAGNOSIS               ≈24-48 hours and is added to maintenance
           potential.                                                               rates.
                                               Diagnostic Overview                  ○   Shock and severe dehydration often require
           GEOGRAPHY AND SEASONALITY           Because dehydration is unlikely to be a primary   more rapid correction.
           •  Hotter weather in the summer may make a   problem, a diagnostic search for an underlying   ○   Initial bolus administration of crystalloid
             sick animal become dehydrated more rapidly.  cause is always warranted. Simply the history   fluids (initial bolus of 20 mL/kg, repeated
           •  Frozen water bowls in the winter may cause   and physical exam often provides an explanation   as required and not to exceed 90 mL/kg/h
             pets to become dehydrated.        for dehydration.                       in dogs or 60 mL/kg/h in cats) may be
                                                                                      appropriate
           Clinical Presentation               Differential Diagnosis             •  Maintenance rate = 40 mL/kg/24 hours for
           DISEASE FORMS/SUBTYPES              •  Skin tent: old age, thin/emaciated body condi-  large dogs (>10 kg), 60 mL/kg/24 hours for
           Hypertonic, isotonic, or hypotonic dehydration  tion (false increase), obesity (false decrease)  cats and small dogs (<10 kg)

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