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275.e2  Draining Tracts, Cutaneous


            extraction using blunt dissection is recom-  Recommended Monitoring  Technician Tips
            mended. Antiinflammatory drugs may ease   Visual assessment of healing  The use of a compound microscope to detect
  VetBooks.ir  •  There is no proven effective medical treat-   PROGNOSIS & OUTCOME  with their characteristic long tails is the key
            removal.
                                                                                 the presence of the unique first-stage larvae
            ment; surgical extraction is recommended.
                                                                                 to diagnosis.
            Experimental treatments include niridazole
            12.5 mg/kg  PO  q  12h  for  10  days,  or   Excellent prognosis if the parasite is surgically   Client Education
                                              extracted and no portions remain in situ
            thiabendazole  50 mg/kg  PO  q  24h  for  2                          Dogs should not be allowed to roam freely to
            to 3 days.                         PEARLS & CONSIDERATIONS           avoid contact with infested water.
           •  A single worm is contained in each ulcerative
            lesion. After the entire gravid female worm is   Comments            SUGGESTED READING
            extracted, healing should take place quickly.  •  These worms are singular in their appearance   Beyer TA, et al: Massive Dracunculus insignis infection
           •  Ivermectin or fenbendazole for 7 to 10 days   in ulcerated skin lesions.  in a dog. J Am Vet Med Assoc 214:351, 366-368,
            can interrupt infection if given within 90   •  Although this nematode is rare, it is easy to   1999.
            days, but early recognition of infection is   diagnose.
            not possible.                     •  D. insignis is closely related to the human   ADDITIONAL SUGGESTED
                                                scourge, D. medinensis, the human Guinea   READINGS
           Chronic Treatment                    worm,  the  “serpent  on  the  stick,”  or  the   Johnson GC: Dracunculus insignis in a dog. J Am
           As needed for dermatologic complications:  serpent of the staff of Aesculapius, the symbol   Vet Med Assoc 165:533, 1974.
           •  Secondary bacterial infection     of the medical/veterinary professions.  Panciera  DL,  et  al:  Dracunculus insignis infection
           •  Cellulitis                      •  The old school/Old World therapy of remov-  in a dog. J Am Vet Med Assoc 192:76-78, 1988.
           •  Culture and sensitivity of skin lesion with   ing D. medinensis in humans is to tie the   AUTHOR: Charles M. Hendrix, DVM, PhD
            appropriate antimicrobial therapy   worm to a small stick and gradually roll the   EDITOR: Joseph Taboada, DVM, DACVIM
                                                worm up over the course of a few days or
           Behavior/Exercise                    weeks. Dogs are not likely to tolerate this
           An Elizabethan collar may be indicated until   therapy.
           the lesion is healed.
                                              Prevention
           Possible Complications             Prevent dogs from roaming and coming into
           Breaking the friable body of the female worm in   contact with freshwater aquatic environments
           situ and not being able to recover the remnants   containing Cyclops species harboring infective
           of the parasite                    larvae of D. insignis.




            Draining Tracts, Cutaneous                                                             Client Education
                                                                                                         Sheet


            BASIC INFORMATION                 ASSOCIATED DISORDERS               •  Exudate  from  the  tracts  may  be  serous,
                                              •  Frequently associated with cutaneous nodular   serosanguineous, or purulent. Tissue granules
           Definition                           disease                            (e.g., actinomycosis, actinobacillosis, nocar-
           A fistulous connection between an area of   •  May be associated with additional systemic   diosis, and bacterial pseudomycetoma) may
           subcutaneous or deeper soft-tissue inflammation   signs, depending on the cause  be found in the exudate.
           and the skin surface
                                              Clinical Presentation              Etiology and Pathophysiology
           Epidemiology                       DISEASE FORMS/SUBTYPES             Infectious causes are often the result of direct
           SPECIES, AGE, SEX                  •  Infectious                      inoculation of the organism into the subcu-
           Varies, depending on cause         •  Noninfectious                   taneous tissue by penetrating injury. Foreign
                                              •  Neoplastic                      material often remains as a sequestrum at
           RISK FACTORS                                                          the site of a penetrating wound, leading to
           Penetrating injuries, chronic exposure of the   HISTORY, CHIEF COMPLAINT  draining tracts. Plant awns, porcupine quills,
           skin to trauma or moisture, wound con-  There may be a history of a previous penetrat-  or other foreign bodies may penetrate through
           tamination, contact with infected individuals,   ing injury, typically associated with infectious   the skin or other orifices (e.g., gastrointestinal
           immunodeficiency syndromes         causes. For all forms/subtypes, a common   tract, respiratory tract) and then migrate to
                                              complaint is a non-healing cutaneous wound   distant body sites. Unlike other infections,
           CONTAGION AND ZOONOSIS             that fails to respond to antimicrobial therapy   systemic  mycoses  (e.g.,  blastomycosis,  coc-
           Pathogens with zoonotic potential are Nocar-  or that recurs after antimicrobial therapy has   cidioidomycosis, cryptococcosis) are acquired
           dia,  Blastomyces,  Sporothrix,  Leishmania,  and     been discontinued.  mainly through inhalation and only rarely
           others.                                                               through direct inoculation. Immunosup-
                                              PHYSICAL EXAM FINDINGS             pressive diseases may increase the risk of
           GEOGRAPHY AND SEASONALITY          •  Lesions may be solitary or multiple.  infection or colonization with opportunistic
           •  In warm, dry climates, grass awns can become   •  Draining  tracts  are  often  associated  with   pathogens.
            penetrating foreign bodies.         cutaneous nodules (fungal or bacterial   •  Bacterial  (including  feline  subcutaneous
           •  Some infectious causes (including systemic   granuloma, idiopathic sterile pyogranuloma/  abscesses, actinomycotic infections  [Acti-
            fungal infections) are endemic to geographic   granuloma, sterile nodular panniculitis).  nomyces, Nocardia], Streptomyces griseus,
            regions.                          •  Lesions may or may not be painful.  Dermatophilus congolensis, actinobacillosis,

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