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280   Dystocia



            Formulas for Predicting Gestational Age and Days Before Parturition
  VetBooks.ir  Gestational Age in Dogs (± 3 Days)*  Gestational Age in Cats (± 2 Days)*
            Less Than 40 Days
                         †
                                                  CRL = 0.2423 × GA − 4.2165
            GA = (6 × GSD) + 20
            GA = (3 × CRL) + 27
            Greater Than 40 Days †
            GA = (15 × HD) + 20                   GA = 25 × HD + 3
            GA = (7 × BD) + 29                    GA = 11 × BD + 21
            GA = (6 × HD) + (3 × BD) + 30
            Days Before Parturition ‡
            DBP = 65 − GA                         DBP = 61 − GA
                                                                                 DYSTOCIA  Uterine  contractions  are  being
           *Gestational age (GA) is based on days after the luteinizing hormone (LH) surge in the dog and days after breeding in the cat.  recorded from this prepartum bitch using veterinary
           † Gestational sac diameter (GSD), crown-rump length (CRL), head diameter (HD), and body diameter (BD) measurements are in centimeters.  tocodynamometry.
           ‡ Number of days before parturition (DBP) is based on 65 ± 1 days after the LH surge in the dog and 61 days after breeding in the cat.
           Modified from Nyland TG, et al: Small animal diagnostic ultrasound, ed 2, Philadelphia, 2002, Saunders.
           •  Minimize fetal stress; neonatal death (fading   ○   Although most dams are eucalcemic,   ○   Elevation of the bitch’s forequarters can
            puppy/kitten) during the first week of life   the benefit of calcium administration   assist in manipulation of the fetus in the
            is related to stress during labor and the   on myometrial contractility is still seen,   birth canal.
            immediate postpartum period.          suggesting a cellular or subcellular effect.
           •  Avoid fetal or maternal mortality.  •  Oxytocin                    Chronic Treatment
           •  Preserve  the  reproductive  capacity  of  a   ○   Give 10-15 minutes after administration   Medical therapy for dystocia,  based on the
            valuable dam.                         of calcium if delivery has not occurred.  administration of calcium gluconate and
           •  Ovariohysterectomy at the time of cesarean   ○   The administration of oxytocin increases   oxytocin, can be directed and tailored based
            section is not advised unless indicated by   the  frequency  of  uterine  contractions,   on the results of tocodynamometry.
            the condition of the uterus (necrotic,   whereas  the  administration  of  calcium
            hemorrhagic) because surgery/anesthesia   increases their strength.  Drug Interactions
            is  prolonged,  hypovolemia  is  exacerbated,   ○   Oxytocin  (10  USP  units/mL)  is  most   Calcium is given before oxytocin in most cases,
            and  lactation without  estrogen can  be   effective at mini doses: start with 0.25   improving contractile strength before increasing
            problematic.                          units/dose SQ or IM to a maximal dose   frequency of contractions.
                                                  of 4 units per bitch or 1 unit per queen.
           Acute General Treatment                IV oxytocin is not advised in the bitch   Possible Complications
           •  Supportive:  intravenous  (IV)  balanced   or queen.               •  Hypercalcemia-induced  arrhythmias  can
            electrolyte  solution  with 5% dextrose if   ○   The frequency of oxytocin administration   result if calcium gluconate is given intrave-
            appropriate (dam is often hypovolemic,   is dictated by the labor pattern, and it is   nously at too rapid a rate.
            dehydrated, or hypoglycemic)          generally not given more frequently than   •  Fetal hypoxia secondary to placental compres-
           •  Evaluate  indications  for  medical  therapy     every 30-60 minutes.  sion  during  uterine  contractions  induced
            (p. 1415).                          ○   Uterine contractions compromise placental    by parenteral oxytocin administration,
            ○   Without tocodynamometry, evaluation   blood flow and cause fetal hypoxia. Exces-  particularly if given inappropriately (e.g.,
              of fetal heart rates before and after   sive contractions (due to uterine hyperto-  too early in labor, when fetal obstruction
              administration of calcium gluconate   nicity, overdosage of oxytocin, obstruction)   is present, if uterine torsion is present, too
              and oxytocin is important.  Worsening   can compromise fetal survival. Uterine   frequently) or at excessive doses
              bradycardia dictates surgical intervention.  relaxation between contractions allows   •  Uterine  rupture,  with  fetal  and  maternal
           •  Calcium: calcium gluconate 10% solution   normal placental blood flow to resume.  morbidity and mortality if ecbolic agents
            (≈10 g/100 mL  solution,  or  0.465 mEq   ○   Absolute contraindications to oxytocin   (oxytocin)  are  given  excessively,  inap-
              2+
            Ca /mL)                               therapy: fetal obstruction in any part of   propriately (too early in labor, when fetal
            ○   Give first (before oxytocin); even if   the uterus or birth canal, uterine torsion,   obstruction is present, if uterine torsion
              eucalcemic (see below)              uterine laceration or rupture.   is present, too frequently, too rapidly),
            ○   Given SQ at 1 mL/4.5 kg (10 lb) body   •  Persistence  of  a  fetus  in  the  birth  canal   or when the uterine wall is compromised
              weight as indicated by the strength of   beyond  5-10  minutes  warrants  assisted   or torn
              uterine contractions, usually not more   delivery.
              frequently than every 4-6 hours during   ○   Placental separation and the potential for   Recommended Monitoring
              the second stage of labor. CAUTION:   fetal hypoxemia are likely.  •  Progression  of  labor  with  viable  neonates
              large volumes of calcium gluconate   ○   CAUTION:  Traction applied to a fetus   delivered
              given subcutaneously may cause local   retained in the birth canal must be very   •  Using real-time transabdominal ultrasonog-
              irritation or even skin necrosis; doses >   gentle to avoid fetal trauma.  raphy or a  fetal Doppler, fetal heart rates
              6 mL should be divided. More concen-  ○   Traction is advised only if the veterinarian   should be > 180-200 beats/min with only
              trated forms of calcium gluconate are not     can position his/her fingers around the   transient decelerations.
              advised.                            fetal shoulders or hips for gentle traction   •  Sustained fetal heart rates < 180 beats/min
            ○   Intravenous use: generally unnecessary   in a downward direction along the plane   are associated with fetal distress.
              unless systemic signs of severe hypocal-  of the vagina and vestibule.  •  Continued  uterine  monitoring  using
              cemia  are  present;  see  Hypocalcemia,   ○   Lubrication  delivered  by  a  red  rubber   tocodynamometry,  showing  continuation
              (p. 515) for signs of hypocalcemia and   catheter and water-soluble lubricant jelly   and progression of appropriate contractile
              intravenous calcium gluconate doses.  can be helpful.                strength and frequency

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