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318   Eyelid Defects: Trauma, Masses


           •  A premium, highly digestible maintenance    PEARLS & CONSIDERATIONS  Technician Tips
            diet is sufficient.               Comments                           Serum  TLI  assays  are  species  specific,  and
  VetBooks.ir  Possible Complications         •  Some patients may not respond to enzyme   species designation can lead to a false diagnosis
                                                                                 submitting a serum sample with the incorrect
                                                replacement therapy and cobalamin supple-
                                                                                 of EPI.
           Enzyme  supplementation  can lead  to oral
           bleeding in ≈10%-20% of patients:
                                                ○   Many of these patients have concurrent
           •  Oral  bleeding  will  stop  in  most  of  these   mentation alone.  SUGGESTED READING
            patients after a reduction of the dose.  small-intestinal  disease  (i.e.,  small-  Steiner JM: Exocrine pancreas. In Steiner JM, editor:
           •  Patients  rarely  develop  bleeding  diathesis   intestinal dysbiosis and/or inflammatory   Small animal gastroenterology, Hannover, Germany,
            due  to  vitamin  K  deficiency,  which  must   bowel disease).        2008, Schlütersche Verlagsgesellschaft, pp 283-306.
            be treated with vitamin K supplementation.  ○   If concurrent disease  cannot be  identi-
                                                  fied, gastric acid inhibition can be tried   AUTHOR: Jörg M. Steiner, Dr. med. vet., PhD,
           Recommended Monitoring                 (omeprazole 0.7-1.0 mg/kg PO q 12h has   DACVIM, DECVIM, AGAF
                                                                                 EDITOR: Keith P. Richter, DVM, MSEL, DACVIM
           Body weight and fecal quality          been most useful).
                                              •  Fresh-frozen raw pancreas can also be used
            PROGNOSIS & OUTCOME                 for  enzyme  replacement  therapy  (1-2 oz
                                                [30-60 g]  of  ground  raw  pancreas  equals
           Most patients with EPI respond to therapy and   about 1 tsp of powdered pancreatic extract).
           have a normal life.




            Eyelid Defects: Trauma, Masses                                                         Client Education
                                                                                                         Sheet


            BASIC INFORMATION                 Eyelid mass:                           the palpebral conjunctiva associated with
                                              •  Blepharitis (eyelid inflammation)   the meibomian gland.
           Definition                         •  Conjunctivitis                  •  Ocular discharge, blepharospasm, conjunc-
           Eyelid trauma is associated with any injury   •  Corneal ulceration     tivitis, keratitis if mass irritating the eye
           to the eyelid predisposing to inflammation or   Clinical Presentation  •  Eyelid hemorrhage
           laceration. Eyelid masses are very common and                         •  Lagophthalmos (incomplete closure of the
           are associated with neoplastic or inflammatory   HISTORY, CHIEF COMPLAINT  eyelids)
           conditions.                        Eyelid trauma:
                                              •  Witnessed traumatic event       Etiology and Pathophysiology
           Synonyms                           •  Swollen eyelid(s) (blepharedema)  •  Eyelid trauma is generally associated with
           •  Chalazion:  hordeolum,  meibomian  gland   •  ± Eyelid laceration    blunt trauma, fight with other animal, pen-
            cyst                              Eyelid mass:                         etration by sharp objects, or self-mutilation
           •  Meibomian glands: tarsal glands, palpebral   •  Growth on eyelid and/or eyelid margin  (pawing at eye).
            glands                            •  Persistent or intermittent bleeding of eyelid  •  Eyelid mass (neoplastic)
                                              •  Signs  of  ocular  pain  if  mass  is  large  and   ○   Common in dogs; most are benign.
           Epidemiology                         causing conjunctival and/or corneal irritation  ○   Rare in cats; most are SCC (malignant)
           SPECIES, AGE, SEX                  •  Ocular discharge                    or mast cell tumors.
           •  Dogs and cats                                                        ○   Similar to those of the skin; arise from
           •  Eyelid trauma may occur at any age.  PHYSICAL EXAM FINDINGS            epithelial, mesenchymal, and melanogenic
           •  Eyelid mass: average age 9-10 years (eyelid   Eyelid trauma (some or all of the following):  cells
            neoplasia, dogs) but depends on type of mass  •  Blepharedema          ○   In  dogs,  82%  of  eyelid  neoplasms  are
                                              •  Eyelid laceration (partial or full thickness)  sebaceous adenomas,  papillomas, or
           GENETICS, BREED PREDISPOSITION     •  Blepharospasm                       melanomas.
           •  Eyelid  trauma:  more  common  in  young   •  Ocular discharge/hemorrhage  ○   Sebaceous  gland  tumors  (sebaceous
            animals,  outdoor  animals,  and  sporting   •  Conjunctival hyperemia/edema (chemosis)  adenoma, sebaceous epithelioma,  and
            breeds of dogs                    •  Keratitis (ulcerative or nonulcerative)  sebaceous adenocarcinoma) arise from
           •  Eyelid mass (dogs): more common in American   Eyelid mass (some or all of the following):  the meibomian glands.
            cocker spaniel, boxer, poodle, golden retriever,   •  Mass located along eyelid margin or adjacent   •  Focal  eyelid  inflammation:  a  chalazion  is
            Labrador retriever, English springer spaniel,   to margin of eyelid    a pyogranuloma associated with retained
            beagle, collie, Siberian Husky, and English setter  •  Size, location, and appearance vary with type   meibomian gland secretions.
                                                of mass
           RISK FACTORS                         ○   Neoplasm associated with the meibomian    DIAGNOSIS
           Excessive sunlight and white hair in the   gland appears  as an  irregular,  raised,
           periocular region predispose to squamous cell   variably sized mass  ± pigment on the   Diagnostic Overview
           carcinoma  (SCC),  the  most  common  eyelid   eyelid margin that may extend into the     •  The diagnosis of eyelid trauma is suspected
           neoplasm in cats.                      eyelid.                          based on the presence of blepharedema and/
                                                ○   SCC appears as an erosive, ulcerated mass   or acute blepharitis with or without ocular
           ASSOCIATED DISORDERS                   along the eyelid, often near the medial   discharge/hemorrhage.
           Eyelid trauma:                         canthus.                       •  The diagnosis of an eyelid mass is suspected
           •  Corneal/scleral trauma            ○   Chalazion  (meibomian  gland  cyst)  is  a   based on the presentation of a mass-type
           •  Uveitis                             smooth, raised, yellow to white mass on   lesion or swelling adjacent to or along the

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