Page 839 - Withrow and MacEwen's Small Animal Clinical Oncology, 6th Edition
P. 839

Index  817


           Carcinoid, 462                      Cell division                       Chemotherapeutic agent (Continued)
            sites for, 137                      anticancer drugs and, 182           antimicrotubule agent, 194–195
                                                phases of, 36
                                                                                      taxanes, 195
           Carcinoma, 63
  VetBooks.ir  immunohistochemical markers/panels for,   Cell kill, ablative techniques for, 169  antitumor antibiotics, 192–193
                                                                                      vinca alkaloids, 195
                72t–73t
                                                cryoablation, 169
            in spinal cord, 666t               Cell mutation, 1                       doxorubicin, 192–193
           Carcinoma in situ, 169–170          Cell proliferation, immunohistochemistry   mitoxantrone, 193
           Carcinomatosis, ultrasonography of, 115f  and, 71                        L-asparaginase, 197
           Carcinosarcoma (malignant mixed mammary   Cellular gigantism, 131        effects of, 300–301
              tumor), 609                      Cellular oncogene (c-onc), 41        “extralabel” manner for, 345
           Carotenoid, 309                     Cellular senescence, 46–47           hydroxyurea, 196–197
           Carprofen, 293t–294t                Cellularity, 129                     pharmacologic activity and
           Carrisyn (Acemannan), 24             molecular mechanism for, 69t            chemosensitivity of, 184f
           Case-control study design, 85–86    Central nervous system tumor, 287t   platinums, 196–197
           Caspase 8, 39                       Central sensitization                therapeutic index for, 182–183
           Caspase cascade, 53                  N-methyl-D-aspartate antagonist and, 295  topoisomerase inhibitors, 195–196
           Cationic lipid-DNA complex (CLDC), 237  of pain, 290                       epipodophyllotoxins, 196
            use of, 237                        CEP. see Circulating endothelial progenitor   tumor cell resistance to, 185–186
           Cavity effusion, 126–127               cell                             Chemotherapy
            tumor metastasis/exfoliating       Cerebrospinal fluid analysis         cancer, 182–208
                into, 145                       of intracranial tumors, 662         in canine osteosarcoma, 542–544, 543t
           cBMMCs. see Canine bone marrow-derived   of spinal cord tumors, 668        gross metastatic disease, 546
              mast cells                       Ceruminous gland, 360                cell specificity of drugs in, 183f
           CD4+ T-cell, 233                    Ceruminous gland adenocarcinoma, 360–361,   clinical trials for, 266–268
            adoptive T-cell transfer and, 241–242  360f                             cutaneous papillomavirus and, 353
           CD8+ T-cell, 233                     metastatic potential of, 360–361    for digital malignant melanoma, 362
           CD44, 54                             survival of, 361                    for feline sarcomas, 423–424
           CDK. see Cyclin-dependent kinase    Ceruminous gland adenoma, 360        intent/goals of, 183
           CDKs/cyclin complex, 36–37          Ceruminous gland cyst, 360, 360f     for intestinal tumor, 467
           CEA. see Carcinoembryonic antigen   Cervical cancer, HPV and, 26         for intracranial tumors, 662–663
           CEC. see Circulating endothelial cell  Cesium-137 teletherapy, 630       lymphoma remission and, 190f
           Cell                                CGH. see Comparative genomic hybridization  for mast cell tumors, 391
            from bladder mass, 129f            Chance error, 343                    for nasal planum, cancer of, 494
            diagnostic quality of, 129         Checkpoint, 37–38                    for nasal planum SCC, 357–358
            keratinization of, 133             Chemical carcinogenic                neutrophil patterns after, 187f
            mutation of, 7                      cyclophosphamide, 15                for oral melanoma with radiation therapy,
            proliferation of, 4–9               environmental tobacco smoke, 14         374–376
            from pulmonary/transitional cell    observational studies for, 92       for oral tumors, 440
                carcinoma, 130f                 pesticides, herbicides, and insecticides, 15  for orbit and optic nerve tumors, 684
            replication of, 46–47              Chemistry, manufacturing, and control   for renal lymphoma, 652
           Cell adhesion molecule (CAM), 54       (CMC), 345                        for soft tissue sarcomas, 416
           Cell-cell anchorage, 53             Chemistry profile, for intestinal    for spinal cord tumors, 668
           Cell-cell contact, 53                  tumors, 463                       surgery and, 170
           Cell cycle                          Chemodectomas, 137                   for urinary bladder tumors, 651
            arrest, 37–38                      Chemoembolization, of interventional   Chemotherapy-induced toxicity
              cause of, 39                        oncology, 177–179                 cumulative/chronic effects of, 187
            checkpoint, 37–38                  Chemokine, 54                        delayed affects of, 187
            chemotherapeutic agents and, 183f  Chemosensitivity, 184                guidelines for, 187t
            control of, 36–37                   processes involved in, 184f        Cherry eye, 675–676
            cyclin-dependent kinases and, 36–37  profiling, 198                    Chloracetate esterase, 129
            DNA synthesis and, 210             Chemotherapeutic agent              Chlorambucil, 191
            p53 and, 38f, 41f                   alkylating agents, 190–192         Chloro-aluminum sulfonated phthalocyanine-
            phase of, 36, 37f                     dacarbazine, 192                    based PDT, 169–170
            redistribution and reoxygenation      nitrogen mustards, 190–191       Cholangiocarcinoma, 455–456, 456f
                of, 211                           nitrosoureas, 191–192            Chondrocytic tumor, 140–141
           Cell death                             procarbazine, 192                Chondroid matrix, 130
            alpha/beta model for, 214f          antimetabolites, 193–194           Chondrosarcoma (CSA)
            alternative methods of radiation, 211  actinomycin D, 193               in cats, 555
            apoptosis and, 39                     cytosine arabinoside, 193–194     in dogs, 550–551
            autophagy and, 6                      5-fluorouracil, 194               fine-needle aspiration of, 140f
            evasion of, 46                        gemcitabine, 194                  in spinal cord, 666t
            ionizing radiation and, 209           methotrexate, 193–194            Choroid plexus tumors, 658t
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