Page 855 - Withrow and MacEwen's Small Animal Clinical Oncology, 6th Edition
P. 855

Index  833


           Oropharyngeal cancer, 432           Pain (Continued)                    Papillomavirus, 19–21
           Orthovoltage radiation, carcinogenesis from,   behavior changes, 288, 290t  in cats, 21–22
              215
                                                                                      viral plaques/fibropapillomas, 353
                                                  clinical metrology instruments in,
  VetBooks.ir  Orthovoltage x-ray, 215            palpation, 288                    in dogs, 19–21
                                                      288–289, 291t
                                                                                    polymerase chain reaction and, 353
           Osteoblast, alkaline phosphatase and, 129
           Osteocartilaginous tumor, 505          physical examination in, 288      prevalence of, 356
           Osteoid, 130                           quantitative sensory testing in, 290  replication of, 352
           Osteomas, 448, 552                     staff/owner involvement in, 288–289  squamous cell carcinoma and, 353
            characteristics of, 140             levels of, 288–289                 Papovaviridae, 19
           Osteosarcoma, 18–19                  neurobiologic signature of, 297    Paracetamol (acetaminophen), 292t
            characteristics of, 140             tumors associated with, 287t       Paragangliomas, 573
            cytoreductive surgery for, 169     Pain management, 286                Paranasal sinuses, tumor of, 504
            ezrin expression and, 51            acupuncture for, 298               Paraneoplastic syndrome (PNS),
            fine-needle aspiration of, 140f     analgesics for, 292t                  98–112, 463
            incidence rates of, 85              approaches to, 288                  causes of, 98
            neutering/spaying and, 92           drugs and strategies for            definition of, 98
            of oral cavity, 435                   acetaminophen, 295                tumors associated with, 99b
            prognosis of, 444                     anticonvulsant drugs, 296         weight loss and, 98
            sex hormones and, 92                  bisphosphonate, 297              Parathyroid adenomas, 581
            in spinal cord, 666t                  N-methyl-D-aspartate antagonist,   Parathyroid hormone-related protein
           Ovarian adenocarcinoma, 598                295–296                         (PTHrP), 632
           Ovarian cancer, 50                     NSAIDs, 290–295                   hypercalcemia of malignancy and, 100
           Ovarian seminomas, 598                 opioids, 295                      tumor-associated, 100
           Ovarian-steroid tumor, 598             sodium channel blockade, 296     Parathyroid tumors, 580–582
           Ovarian tumor, 597–600                 steroids, 296–297                 characteristics of, 137
            comparative aspects of, 599–600       tramadol, 295                    Parenchymal cell, 62
            diagnostic techniques and workup for, 599,   tricyclic antidepressants, 296  Parenteral nutrition
                599f                            glucocorticoid for, 296–297         formulation for, 305–306
            incidence of, 597                   importance of, 288                    form for, 306f–307f
            ovariohysterectomy for, 599         pharmacologic desensitization strategy for,   preparation of, 306
            pathology and natural behavior of, 597–598  298                         glucose and lipid proportions in, 306
              canine ovarian tumors, 597–598    pharmacologic therapy as, 290–297   high protein/high calorie products, 305t
              feline ovarian tumors, 598        radiation therapy for, 297–298      substrates for, 305–306
            prognosis for, 599                 Pain syndrome, 296                   types and complications of, 305
            therapy for, 599                   Palliative care                     PARG. see Poly adenosine diphosphate ribose
           Ovariohysterectomy (OHE)             for intracranial tumors, 662, 663f    glycohydrolase
            hyperadrenocorticism after, 598     transitioning to, 317              Parosteal osteosarcoma, 550, 550f
            mass at uterine stump after, 600f  Palliative chemotherapy, 183        PARP. see Poly adenosine diphosphate ribose
            ovarian tumors and, 599            Palliative radiation therapy, 215      polymerase
           Oxygen, irradiation and, 210         for primary and metastatic bone cancer   Partial pancreatectomy, for canine insulinoma,
           Oxygen cycle, DNA synthesis and, 210     pain, 547                         583–584
           Oxygen depletion, 37–38             Palliative surgery, considerations for,    Partial parenteral nutrition (PPN), 305
                                                  168–169                           formulation sheet for, 307f
           P                                   Pamidronate, 292t                   Particle bombardment, 252t
           p21, 39                             Pancreatic beta-cell tumors, 582–584  Partnership, in patient care, 314
            canine osteosarcoma and, 525        in cats, 584                       Pasireotide, for canine pituitary-dependent
           p53, 37–38, 43–44                    in dogs, 582–584                      hypercortisolism, 567
            canine osteosarcoma and, 525       Pancreatic carcinoma, 105           Passive diffusion, chemotherapeutic agent
            cell cycle control and, 38f, 41f   Pancytopenia, 629                      uptake and, 184
            expression, 39                     Papanicolaou staining, 128–129      Paternalism, 311
            feline cutaneous SCC and, 354      Papilloma                           Pathology laboratory, categories of errors at,
            gene therapy and, 254               clinical features of                  75
            as genomic guardian, 38               in cats, 22                      Patient-reported outcomes (PROs), 288
            testicular tumors and, 628            in dogs, 20                      PBMC. see Peripheral blood mononuclear cell
           Paclitaxel, 185                      development of                     PCNA. see Proliferating cell nuclear antigen
            clinical use of, 195                  in cats, 21–22                   PCR. see Polymerase chain reaction
            pharmacology of, 195                  in dogs, 19–21                   PCR-based techniques, detection of mutations
           PAE. see Prostatic artery embolization  diagnosis of, 22                   and novel genes and assessment of
           Pain                                 treatment of, 22                      clonality, 147–151
            assessment of                      Papillomatosis                      PCR for antigen receptor rearrangement
              activity in, 289–290              treatment of, 21                      (PARR) assay, 150
              approaches to, 289f               types and clinical features of, 20  application of, 150–151
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