Page 863 - Withrow and MacEwen's Small Animal Clinical Oncology, 6th Edition
P. 863

Index  841


           Tumor cell (Continued)              Type II/β error (false negative), 343  Uterine tumors (Continued)
            genetic instability and, 7         Tyrosinase, 362, 376                 pathology and natural behavior of, 600
            GLUT-1 and, 9
                                                                                    prognosis for, 600
                                               Tyrosine kinase (TK), 257–258
  VetBooks.ir  heat shock protein 90 inhibitor and, 271  Tyrosine kinase inhibitor (TKI), 197–198  UTIs. see Urinary tract infections
                                                                                    therapy for, 600
            microenvironment of, 49–50
                                                molecular profiling and, 347
              adaptive evolution and, 9–10      role of, 146
              immunosuppressive barrier, 9     Tyrosine kinase receptor, types of, 146  V
              secondary life, 54                cancer association and, 261t       Vaccination
            proteasome inhibition effect on, 270–271  Tyrosine protein kinase MET, canine   for feline leukemia virus, 24–25
            self-renewal of, 10–11                osteosarcoma and, 526             fibrosarcoma and, 93
            spheres of, 11f                    TZL. see T-zone lymphoma             for oral melanoma, 375–376
            trapping of, 54                    T-zone lymphoma (TZL), 700t         Vaccine-associated fibrosarcoma, 138f
           Tumor cell kill, 169                                                    Vaccine injection site, observational studies for
           Tumor cell line panel, 183–184      U                                      cancer at, 87t–91t
           Tumor cell lysate vaccines, 239     Ubiquitin-proteasome pathway (UPP), 270  Vaginal and vulvar tumors
           Tumor cell resistance, 185–186      Ulnar transposition, for canine osteosarcoma,   diagnostic techniques and workup for, 602
           Tumor cell sensitivity, 183–185        538                               extraluminal versus intraluminal, 601
           Tumor endothelial cell, 264         Ultrasonography, 113–115             history and clinical signs of, 602
           Tumor excision, levels of, 164, 165f–166f  for adrenal gland neoplasia, 571–572  incidence of, 600–601
           Tumor grading                        for adrenal medullary tumors, 573   pathology and natural behavior of,
            differentiation and, 67             of carcinomatosis, 115f                 601–602
            importance of, 61                   of interventional oncology, 174     prognosis for, 602
            reflecting molecular mechanisms,    for intestinal tumors, 463–464, 464f  surgical excision of
                67–69, 69t                      of multifocal nodule, 115f            of intraluminal tumors, 602
            for skin/subcutaneous tissue tumor, 355  radiography versus, 113–114      with ovariohysterectomy, 602
           Tumor growth fraction,               of soft tissue mass, 116f           types of, 600–602
              immunohistochemistry and, 71     Ultrasound-guided ethanol ablation, for   Vaginal leiomyoma, 602
           Tumor heterogeneity, 50                primary hyperparathyroidism, 582  Validation study, 92
           Tumor hormone receptor, 606–607     Ultrasound-guided percutaneous ethanol   Valproic acid (VPA)
           Tumor immunosuppression, 233           injection, for feline hyperthyroidism, 580  efficacy of, 270
           Tumor-induced mobilization, 54      Ultrasound-guided radiofrequency ablation   role of, 270
           Tumor-infiltrating lymphocyte          (RFA), for primary hyperparathyroidism,   Vascular collapse, 263–264
              transfer, 242                       582                              Vascular endothelial cell tumor, as
           “Tumor-initiating cell” hypothesis, 10–11  Ultraviolet irradiation, 16     conjunctival tumor, 675
           Tumor margin, assessment of, 61, 69–70  skin cancer and, 352            Vascular endothelial growth factor (VEGF)
           Tumor-node-metastasis, 354          Undifferentiated malignancy, 447     blood vessel creation and, 47–48
            for oral melanoma, 368f            UPP. see Ubiquitin-proteasome pathway  in canine osteosarcoma, 533
           Tumor-promoting inflammation, 7–8   Urban environment, 15–16             in canine sinonasal tumors, 495
            neoplastic progression and, 49     Ureteral stenting, for malignant urethral   dendritic cells and, 233–234
           Tumor seeding, 159                     obstruction, 175, 176f            seminomas and, 628
           Tumor sensitivity, 198              Urethral stent placement, for malignant   Vascular endothelial growth factor receptor
           Tumor stem cells, 211                  urethral obstruction, 175           (VEGFR)
           Tumor-stromal interaction, 54       Urethral tumor, 652                  expression of, 54, 258
           Tumor suppressor gene, 41t          Urinary system tumors, 645–656       growth signaling pathways and, 264
            apoptosis and, 6                    canine urinary bladder tumors, 645–652  signaling, 258
            cancer and, 43–44                   feline urinary bladder tumors, 652  toceranib and, 263
            canine osteosarcoma and, 525        renal tumor                        Vascular endothelial growth factor-A
            disabling of, 1                       canine, 652–653                     (VEG-A), role of, 6
            epigenetic methylation, 10            feline, 653                      Vascular endothelium tumor, 138–139
            retinoblastoma and, 43              urethral tumor, 652                Vascular ligation, 167
            role of, 5–6                       Urinary tract infections (UTIs), transitional   Vascular normalization, 6–7
            tumor formation and, 43               cell carcinoma and, 651–652      Vascularized ulnar transposition technique,
           Tumor vaccine, 239–240              Urogenital system tumor, 134–135       538
            approaches to, 239–240             Uroplakin III, 646                  Vasculogenesis, 263
            tumor antigens and, 239            Urticaria pigmentosa, 397           Vasculogenic mimicry, 53
            using viral vector vaccines, 240   Uterine stump, 600                  Vector targeting, 253f
           Tumorigenic cell, as cancer stem cell, 50  mass at, 600f                Vedaprofen, 293t–294t
           Tunneling, needle core biopsy and, 159  Uterine tumors, 600             Vegetable, transitional cell carcinoma and,
           TVT. see Transmissible venereal tumor  diagnostic therapeutics and workup for, 600  645–646
           Type I research, 344–345             history and clinical signs of, 600, 600f  VEGF. see Vascular endothelial growth factor
           Type I/α error (false positive), 343  incidence of, 600                 VEGFR. see Vascular endothelial growth
           Type II research, 344–345            ovariohysterectomy for, 600           factor receptor
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