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CHAPTER 15   Disorders of the Nasal Cavity   269


            Results of such testing do not support the diagnosis of a   Breitschwerdt EB, et al. Bartonella species as a potential cause of
                                                                  epistaxis in dogs. J Clin Microbiol. 2005;43:2529.
            specific disease. Usual nonspecific findings include turbi-  Buchholz J, et al. 3D conformational radiation therapy for palliative
  VetBooks.ir  nate erosion, mucosal inflammation, and increased mucus   treatment  of  canine  nasal  tumors.  Vet Radiol Ultrasound.
            accumulation as assessed by nasal imaging and rhinos-
                                                                  2009;50:679.
            copy; neutrophilic or mixed inflammation with bacteria on
            cytology of nasal discharge; and lymphoplasmacytic and/  Fossum TW.  Small  Animal Surgery. 5th ed. St Louis: Elsevier
                                                                  Mosby; 2018.
            or neutrophilic inflammation on nasal biopsy. Nonspecific   Greci V, Mortellaro CM. Management of otic and nasopharyngeal
            abnormalities attributable to chronic inflammation, such as   polyps in cats and dogs. Vet Clin North Am Small Anim Pract.
            epithelial hyperplasia and fibrosis, can also be seen. Sec-  2016;46:643.
            ondary bacterial rhinitis or  Mycoplasma infection may     Gunnarsson L, et al. Efficacy of selemectin in the treatment of nasal
            be identified.                                        mite (Pneumonyssoides caninum) infection in dogs. J Am Anim
                                                                  Hosp Assoc. 2004;40:400.
            Treatment                                            Hartmann AD, et al. Efficacy of pradofloxacin in cats with
            Treatment of idiopathic canine chronic rhinitis is also similar   feline upper respiratory tract disease due to  Chlamydophila
            to that described for idiopathic feline rhinosinusitis (see pre-  felis or  Mycoplasma infections.  J Vet Intern Med. 2008;22:
                                                                  44.
            vious section and Box 15.1). Dogs are treated for secondary   Hawkins EC, et al. Failure to identify an association between
            bacterial rhinitis (as described the earlier in this chapter),   serologic or molecular evidence of  Bartonella spp infection
            and efforts are made to decrease irritants in the environment   and idiopathic rhinitis in dogs. J Am Vet Med Assoc. 2008;233:
            (see feline chronic rhinosinusitis). As with cats, some dogs   597.
            will benefit from efforts to facilitate the draining of nasal   Henn JB, et al. Seroprevalence of antibodies against  Barton-
            discharge by humidification of air or instillation of sterile   ella species and evaluation of risk factors and clinical signs
            saline into the nasal cavity.                         associated with seropositivity in dogs.  Am J Vet Res. 2005;66:
              Although antiinflammatory treatment as described pre-  688.
            viously for cats may be beneficial in some dogs, successful   Holt DE, Goldschmidt MH. Nasal polyps in dogs: five cases
            treatment was originally reported in dogs with lymphoplas-  (2005-2011). J Small Anim Pract. 2011;52:660.
            macytic rhinitis using immunosuppressive doses of predni-  Johnson  LR,  et al.  Assessment of  infectious  organisms  associ-
            sone (1 mg/kg, orally, q12h). A positive response is expected   ated with chronic rhinosinusitis in cats.  J Am Vet Med Assoc.
                                                                  2005;227:579.
            within 2 weeks, at which time the dose of prednisone is   Lappin MR, et al. Antimicrobial use guidelines for treatment of
            decreased gradually to the lowest effective amount. If no   respiratory tract disease in dogs and cats: Antimicrobial Guide-
            response to initial therapy occurs, other immunosuppressive   lines  Working  Group  of  the  International  Society  for  Com-
            drugs such as azathioprine can be added to the treatment   panion Animal Infectious Diseases. J Vet Intern Med. 2017;31:
            regimen (see Chapter 72). Unfortunately, immunosuppres-  279.
            sive treatment is not always effective. If clinical signs worsen   Lappin MR, et al. Use of serologic tests to predict resistance to feline
            during treatment with corticosteroids, the clinician should   herpesvirus 1, feline calicivirus, and feline parvovirus infection
            discontinue therapy and carefully reevaluate the dog for   in cats. J Am Vet Med Assoc. 2002;220:38.
            other diseases.                                      Mathews KG, et al. Computed tomographic assessment of nonin-
              Dogs with severe or nonresponsive signs are candidates   vasive intranasal infusions in dogs with fungal rhinitis. Vet Surg.
                                                                  1996;25:309.
            for rhinotomy and turbinectomy, as described for feline   Papich MG, et al. Cetirizine (Zyrtec) pharmacokinetics in healthy
            chronic rhinosinusitis.
                                                                  cats, Abstract. J Vet Intern Med. 2006;20:754.
            Prognosis                                            Piva S, et al. Chronic rhinitis due to Streptococcus equi subspecies
                                                                  zooepidemicus in a dog. Vet Rec. 2010;167:177.
            The prognosis for idiopathic chronic rhinitis in dogs is gen-  Pomerantz JS, et al. Comparison of serologic evaluation via agar gel
            erally good with respect to improvement of signs and quality   immunodiffusion and fungal culture of tissue for diagnosis of
            of life. However, some degree of clinical signs persists in   nasal aspergillosis in dogs.  J Am Vet Med Assoc. 2007;230:
            many dogs.                                            1319.
                                                                 Rassnick KM, et al. Evaluation of factors associated with survival
                                                                  in dogs with untreated nasal carcinomas: 139 cases (1993-2003).
            Suggested Readings                                    J Am Vet Med Assoc. 2006;229:401.
            Anderson DM, et al. Management of inflammatory polyps in 37   Richards JR, et al. The 2006 American Association of Feline Prac-
              cats. Vet Record. 2000;147:684.                     titioners Feline Vaccine Advisory Panel Report. J Am Vet Med
            Arteaga T, et al. A retrospective analysis of nasal lymphoma in 71   Assoc. 2006;229:1405.
              cats (1999-2006), Abstract. J Vet Intern Med. 2007;21:573.  Schmidt BR, et al. Evaluation of piroxicam for the treatment of
            Berryessa NA, et al. Microbial culture of blood samples and sero-  oral  squamous  cell  carcinoma  in dogs.  J Am Vet Med Assoc.
              logic testing for bartonellosis in cats with chronic rhinitis. J Am   2001;218:1783.
              Vet Med Assoc. 2008;233:1084.                      Sharman M, et al. Muti-centre assessment of mycotic rhinosinusitis
            Binns SH, et al. Prevalence and risk factors for feline  Bordetella   in dogs: a retrospective study of initial treatment success. J Small
              bronchiseptica infection. Vet Rec. 1999;144:575.    Anim Pract. 2010;51:423.
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