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CHAPTER 20   Diagnostic Tests for the Lower Respiratory Tract   293





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                          FIG 20.8
                          Lateral radiograph of a dog with pulmonary carcinoma. An unstructured pattern is
                          present, as is an increased bronchial pattern.


            Lesions  caused  by  parasites,  fungal  infections,  and  some
            eosinophilic lung diseases or idiopathic interstitial pneumo­   BOX 20.6
            nias may be indistinguishable from neoplastic lesions. In the   Differential Diagnoses for Dogs and Cats With Reticular
            absence of strong clinical evidence, malignant neoplasia   (Unstructured) Interstitial Patterns
            must be confirmed cytologically or histologically. If this is
            not possible, radiographs can be obtained again 4 weeks later   Pulmonary Edema (Mild)
            to evaluate for progression of disease.               Infection
              Neoplastic involvement of the pulmonary parenchyma    Viral pneumonia
            cannot be totally excluded on the basis of thoracic radio­  Bacterial pneumonia
            graph findings because malignant cells are present for a   Toxoplasmosis
            while before lesions reach a radiographically detectable size.   Mycotic pneumonia
            The sensitivity of radiography in identifying neoplastic   Parasitic infection (more often bronchial or nodular
                                                                      interstitial pattern)
            nodules can be improved by obtaining left and right lateral   Neoplasia
            views of the thorax.                                  Eosinophilic Lung Disease
              The reticular interstitial pattern is characterized by a   Idiopathic Interstitial Pneumonia
            diffuse, unstructured, lacy increase in the opacity of the pul­  Idiopathic pulmonary fibrosis
            monary interstitium, which partially obscures normal vas­  Hemorrhage (Mild)
            cular and airway markings. Reticular interstitial patterns
            frequently occur in conjunction with nodular interstitial pat­
            terns (also called reticulonodular patterns) and alveolar and
            bronchial patterns (Fig. 20.8).                      interstitial nodular patterns can cause a reticular interstitial
              Increased reticular interstitial opacity can result from   pattern early in the course of disease (see Boxes 20.4 and
            edema, hemorrhage, inflammatory cells, neoplastic cells, or   20.5). This pattern is also often seen in older dogs with no
            fibrosis within the interstitium (Box 20.6). The interstitial   clinically apparent disease, presumably as a result of pulmo­
            space surrounds the airways and vessels, and is normally   nary fibrosis; this further decreases the specificity of the
            extremely small in dogs and cats. With continued accumula­  finding.
            tion of fluid or cells, however, the alveoli can become flooded,
            which produces an alveolar pattern. Visible focal interstitial   Lung Lobe Consolidation
            accumulations of cells, or nodules, can also develop with   Lung lobe consolidation is characterized by a lung lobe that
            time. Any of the diseases associated with alveolar and   is entirely of soft tissue opacity (Fig. 20.9, A). Consolidation
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