Page 92 - Small Animal Internal Medicine, 6th Edition

64 PART I Cardiovascular System Disorders

TABLE 3.3
VetBooks.ir Drugs for Managing Chronic Heart Failure CATS

DOGS
DRUG
Diuretics
Furosemide 1-3 (or more) mg/kg PO q8-24h (long term); 1-2 (or more) mg/kg PO q8-24h; use
use smallest effective dose. In refractory smallest effective dose. See Box 3.1
CHF, several intermittent 2 mg/kg SC for acute CHF recommendations
doses/week, in place of PO doses, may be
helpful (or use torsemide; see text [p. 66]).
See Box 3.1 for acute CHF
recommendations
Torsemide Dose at 1 12 to 1 8 of patient’s total daily Same
furosemide dose; administer in two divided
doses
Spironolactone (0.5-)2 mg/kg PO q24h (or divided q12h) 0.5-1 mg/kg PO q24h (or divided
q12h)
Chlorothiazide 10-40 mg/kg PO q12-48h (start qod with low 10-40 mg/kg PO q12-48h (start qod
dose) with low dose)
Hydrochlorothiazide 0.5-4 mg/kg PO q12-48h (start qod with low 0.5-2 mg/kg PO q12-48h (start qod
dose) with low dose)

ACE Inhibitors
Enalapril 0.5 mg/kg PO q12-24h 0.25-0.5 mg/kg PO q(12-)24h
Benazepril 0.25-0.5 mg/kg PO q(12-)24h 0.25-0.5 mg/kg PO q(12-)24h
Captopril 0.5-2 mg/kg PO q8-12h 0.5-1.25 mg/kg PO q(8-)24h
Lisinopril 0.25-0.5 mg/kg PO q(12-)24h 0.25-0.5 mg/kg PO q24h
Ramipril 0.125-0.25 mg/kg PO q24h 0.125 mg/kg PO q24h
Imidapril 0.25 mg/kg PO q24h —

Other Vasodilators
Hydralazine 0.5-2 (to 3) mg/kg PO q12h (to 1 mg/kg 2.5 (up to 10) mg/cat PO q12h
initial). See Box 3.1 for acute CHF
recommendations
Amlodipine 0.05 (initial) to 0.3(-0.5) mg/kg PO q(12-)24h 0.3125-0.625(-1.25) mg/cat (or
0.1-0.5 mg/kg) PO q24(-12)h
Prazosin 0.05-0.2 mg/kg PO q8-12h 0.25-0.5 mg/cat PO q12-24h
Nitroglycerin 2% ointment 1 4 -1 inch cutaneously q4-6h for 24-48 hours 1 4 - 2 inch cutaneously q4-6h for 24-48
1
1
2
hours
Isosorbide dinitrate 0.5-2 mg/kg PO q(8-)12h —
Isosorbide mononitrate 0.25-2 mg/kg PO q12h —
Positive Inotropes
Pimobendan 0.2-0.3 mg/kg PO q12h; for refractory (stage As for dog, or 1.25 mg/cat PO
D) CHF, could be increased up to q12(-8)h
0.4-0.5 mg/kg q8h
Digoxin PO: 0.003-0.005 mg/kg PO q12h. Decrease 0.007 mg/kg (or of 0.125 mg tab)
1
by 10% for elixir. Maximum: 0.5 mg/day PO q48h 4
or 0.375 mg/day for Doberman Pinschers.
(See Box 3.1 for loading doses)