Page 1547 - Veterinary Immunology, 10th Edition

VetBooks.ir Intrachain bond A bond between two cysteine residues on a single

peptide chain. Because disulfide bonds are short, its effect is to
produce a fold in the peptide chain.

Intraepithelial lymphocytes Lymphocytes, mainly T cells, located
among the epithelial cells in the intestinal wall.

Intron A region inserted within a gene that separates exons and is
not expressed.

Isoform Different molecular forms of a protein that are generated
by differential processing of RNA transcripts of a single gene.

Isogeneic (syngeneic) Genetically identical.

Isograft A graft between two genetically identical animals.

Isotype switching The change in immunoglobulin class that occurs
during the course of the immune response as a result of heavy

chain gene switching.

Isotypes Closely related proteins that arise as a result of gene

duplication. They are found in all animals of a species. Thus the
subclasses of immunoglobulins are actually isotypes.

J

J chain A short peptide that joins units in the polymeric
immunoglobulins IgM and IgA.

Joining (J) gene segment A short gene segment that is located 3′ to
the V gene segments in immunoglobulin and TCR V genes and

codes for part of the variable region.

K

K antigens Capsular antigens of Gram-negative bacteria.

Killer cell See Natural killer cells.

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