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Parasitology  181




































                Figure 3.37  Climatic zones. The climate and topography of a country will determine the range of arthro-
                pod vectors present and therefore allows some prediction of the likely presence or absence of specific
                vector-borne diseases: (A) cool humid zones (continental summer and subarctic); (B) dry zones (desert and
                steppe); (C) warm humid zones (Mediterranean, humid subtropical and west coast regions); (D) tropical
                humid zones (rain forest and savannah). There are a wide range of variations within zones depending on
                the factors such as altitude and vegetation. The map illustrates climatic zones and zoogeographical regions.


                therefore allow an assessment of which proto-  the disease also affects people in the USA.
                zoal diseases and other arthropod transmitted   The symptoms of Chagas disease vary over the
                diseases are likely to occur in a given region.   course of an infection. In the early, acute stage,
                The role of wildlife reservoirs in livestock dis-  symptoms are often mild and usually produce
                ease outbreaks is discussed further in Chapter 9.  no more than local swelling at the site of infec-
                                                         tion. After 4–8 weeks, individuals with active
                                                         infections enter the chronic phase of Chagas
                Trypanosomiasis in humans and            disease that is asymptomatic for 60–80% of
                community engagement
                                                         chronically infected individuals through their
                Trypanosomiasis causes significant human   lifetime. There are various treatment options.
                morbidity and mortality in many parts of the   Antiparasitic treatments given in the acute phase
                developing world. Chagas disease is caused by   of the infection may delay or prevent the devel-
                Trypanosoma cruzi, a parasite spread by blood-  opment of disease symptoms during the chronic
                sucking reduviid bugs (for example, Rhodnius   phase of the disease, but 20–40% of chronically
                prolixus), and is one of the major health prob-  infected individuals may still go on to develop
                lems in South America. Due to immigration,   life-threatening heart and digestive system







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