Page 1011 - Problem-Based Feline Medicine
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46 – THE CAT WITH AGGRESSION  1003


           appropriate acceptable behavior – see aggression when  Pathogenesis
           patted for details (page 1000).
                                                          As with most behavioral conditions the underlying
            ● If the cat shows any sign of aggression then move
                                                          pathogenesis is unknown. There is often an underlying
              away and stop all interactions.
                                                          anxiety component.
            ● Physical punishment should be avoided as that
              will exacerbate the problem.                The cat’s territory may be patrolled and can be marked
            ● Anxiolytic medication may also be needed to treat  by rubbing, bunting and/or spraying to maintain social
              the cat to alter the neurochemical environment.  distance and define hierarchy.
              – Tricyclic antidepressants (TCAs) such as
                                                          The aggression can be intra- and interspecific (between
                amitriptyline (0.5–1 mg/kg PO q 24 h, average
                                                          members of the same species or between other species),
                of 5–10 mg/cat PO q 24 h) or clomipramine
                                                          including people.
                (0.5 mg/kg PO q 24 h) have proven useful in
                some cases.
              – Selective serotonin re-uptake inhibitors (SSRIs)
                                                          Classical signs
                such as fluoxetine (0.5 mg/ kg PO q 24 h) have
                also proved useful and can be easier to administer  The cat exhibits aggression to anyone approaching
                as they are available in a liquid formulation.  or entering its territory and may attack.
              – Benzodiazepines are  generally not recom-
                                                          The behavior may be more marked in entire toms in
                mended as they may disinhibit aggression.
                                                          the breeding season.
              – Blood biochemistry analysis should be done prior
                to medication to determine a baseline especially  Aggression decreases with increased distance away
                for liver and kidney parameters as medications are  from the territory.
                metabolized by the liver and excreted through the
                                                          It is often seen when a new cat is introduced into the
                renal system. These parameters should be
                                                          household or the cat returns from a visit to a cattery
                checked every 6–12 months depending on the age
                                                          or veterinary hospital and now is not recognized by
                and general health status of the cat.
                                                          the other cat.
           The cat may require life-long medication or for pro-
           longed periods of up to 6–12 months. Attempts to slowly
                                                          Diagnosis
           wean off medication may be made.
                                                          Diagnosis is based on a complete behavioral history
           Prognosis                                      and a thorough physical examination.
           The behavior can usually be managed, not cured,
           with owner education and compliance.           Differential diagnosis
           The prognosis is poor if the eliciting stimuli cannot  Other types of aggression should be considered including:
           be defined, the attacks are severe or people cannot  ● Status-related aggression and territorial aggres-
           read the cat’s body language.                     sion may co-exist, however, the contexts in which
                                                             territorial behavior is elicited will be different.
           Punishment tends to aggravate the aggression and
                                                          ● Intercat intermale aggression is seen in entire
           should be avoided at all times.
                                                             males during the breeding season, whereas territo-
                                                             rial aggression may be seen at other times and may
           TERRITORIAL AGGRESSION*                           be exhibited by males and females.
                                                          Cats may exhibit several types of aggression concurrently.
            Classical signs

            ● The aggressive behavior is directed         Treatment
               towards intruders approaching or entering
               into the cat’s established domain.         Avoid situations that may be provocative to avoid
                                                          reinforcing the behavior.
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