Page 1083 - Problem-Based Feline Medicine
P. 1083

51 – THE CAT WITH SKIN LUMPS AND BUMPS  1075


           Diagnosis                                      The metastatic rate has been reported to be as high as
                                                          22%.
           Fine-needle aspirate cytology is  often diagnostic
           showing round cells with metachromatic granules.  Some cats do acquire new primaries.
           Histopathology is usually necessary to diagnose the
           histiocytic form where granules are not prominent.  HEMANGIOMA AND HEMANGIOSARCOMA*
           Extension to regional lymph nodes is not common,
           but any enlarged node should be evaluated at least by  Classical signs
           fine-needle aspirate.
                                                           ● Dark red cutaneous nodule.
           In cats where disseminated disease (spleen or intes-
           tinal forms) is suspected, tests such as hematology,  Pathogenesis
           serum biochemistry, buffy coat smear or bone marrow
           aspirate, coagulation studies, thoracic and abdominal  Hemangiomas are benign tumors of vascular
           radiography and abdominal ultrasonography should be  endothelium. The malignant, anaplastic counterpart is
           considered.                                    hemangiosarcoma.
                                                          Hemangiosarcomas of the nasal planum and eyelid may
           Differential diagnosis                         be solar induced.
           Other cutaneous neoplasms should be considered as  Clinical signs
           differential diagnoses. Differentiation is based on fine-
           needle cytology or histological examination.   Hemaniomas and hemangiosarcomas are very rare in
                                                          cats.

           Treatment                                      In the skin, they usually appear as  red to dark-red
                                                          nodules of varying size.
           For the mastocytic form, surgery is the preferred  ● Spontaneous hemorrhage from the lesions may be
           treatment. Surgical margins need not be as wide as for  a feature.
           canine mast cell tumors (3 cm), since most have a rela-
           tively benign biological behavior. Wider margins are  They may also appear as an ulcerated lesion on the nose.
           necessary in the case of  diffuse mastocytic forms.  Hemangiosarcoma can occur in the subcutaneous and
           Conservative resection is appropriate for the histiocytic  muscular tissue as a soft mass, and there may be a
           form.                                          zone of echymosis surrounding the mass.

           Cats with the splenic form benefit from splenectomy,  Hemangiosarcoma can also occur in visceral organs,
           even though tumor cells may be disseminated.   and rarely the skin lesions may be secondaries to pri-
           Little is know of the efficacy of adjuvant therapy for  mary disease in the viscera.
           mast cell tumors in cats.
                                                          Diagnosis
                                                          Cytological examination may be unrewarding because
           Prognosis
                                                          the cells do not exfoliate well.
           In general, the prognosis for most cats with mast cell  ● Malignant mesenchymal cells may be found at the
           tumors is very good.                              feathered edge of cytology slides.

           Most cats experience long-term control after complete  Definitive diagnosis requires histological examination.
           surgical excision.
                                                          Treatment
           Local recurrence rates for the mastocytic form fol-
           lowing surgery vary up to 24%.                 Surgical resection is the treatment of choice, and for
            ● If the tumor recurs, it usually does so within 6  hemangiosarcomas, as wide a margin as possible
              months of surgery.                          should be taken, preferably greater than 10 mm.
   1078   1079   1080   1081   1082   1083   1084   1085   1086   1087   1088