Page 1089 - Problem-Based Feline Medicine
P. 1089

52. The cat with non-healing wounds



                          Gregory Burton











                           KEY SIGNS
                           ● Erosion, ulceration.
                           ● Nodules or plaques with ulceration or fistulae.
                           ● Serosanguineous to purulent exudate +/- tissue grains.
                           ● Subcutaneous fibrosis.
                           ● Extracutaneous symptoms may be present.




            MECHANISM
                       ● Non-healing wounds occur where there is a failure of re-epithelialization, dermal fibroplasia
                          and or angiogensis.
            WHERE?
                       ● Skin (diseases involving the epidermis, dermis, panniculus and cutaneous blood vessels)
                          and mucocutaneous junctions.
            WHAT?
                       ● Most cats with non-healing skin wounds have infections (mycobacteria, aerobic and/or anaerobic
                          bacteria, or fungi). Neoplasia, allergies, immune-mediated and metabolic diseases are less
                          common.



            QUICK REFERENCE SUMMARY
            Diseases causing non-healing wounds
            ANOMALY

                       ● Cutaneous asthenia (p 1100 - 1101)
                       Congenital disease resulting in hyperextensibility and fragility of the skin. Kittens present with
                       spontaneous tears or necrotic, slow-healing crusted ulcerations.
                       ● Epidermolysis bullosa (p 1101)
                       Congenital epidermal basement membrane disease with signs evident shortly after birth. Skin, foot
                       pad and mouth ulcers particularly at frictional areas. Nail shedding is common.

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