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53 – THE CAT WITH PAW OR PAD PROBLEMS  1113


              for  up to 30 days after negative skin scrapings.
                                                          HYPERTHYROIDISM**
              Stopping too early results in relapses.
            ● Similarly Doramectin at 0.6 mg/kg sc weekly can
                                                           Classical signs
              be used.
                                                           ● Weight loss with polyphagia.
           Leishmania.
                                                           ● Unkempt hair coat.
            ● Successful treatment in cats has not been reported.
                                                           ● Nervous, hyperactive.
                                                          See main reference on page 304 for details (The Cat
           Prognosis                                      With Weight Loss and a Good Appetitie).

           Prognosis varies depending on the type of infection and
           the underlying cause. The recurrence rate is high for  Clinical signs
           bacterial paronychia if there is an underlying immune
                                                          Most commonly there is weight loss despite a raven-
           deficiency.
                                                          ous appetite. More rarely is appetite depressed.
           The prognosis is more guarded for the rarer opportunis-
                                                          Other signs may include tachycardia, polydipsia/
           tic bacterial and fungal infections. Cures are reported
                                                          polyuria, vomiting or diarrhea, and a heart murmur.
           with the use of the imidazole drugs (ketoconazole and
           itraconazole).                                 A palpable thyroid nodule in the neck is present in the
                                                          majority of cats.
                                                          Restlessness and hyperexcitability are often evident.
           HYPERPIGMENTATION (LENTIGO
           SIMPLEX)**                                     An unkempt haircoat and overgrown claws are typical.
                                                          ● The overlong claws catch in floor coverings or click
                                                             on bare floors as the cat walks.
            Classical signs
                                                          Usually occurs in cats older than 8 years of age.
            ● Black asymptomatic spots that gradually
               enlarge and become more numerous.          Diagnosis
            ● Occur in cats with orange coat color.
                                                          A tentative diagnosis is based on history and physical
                                                          examination.
           Clinical signs                                 Increased total thyroxine (T ) levels confirm the diag-
                                                                                4
                                                          nosis. Cats with a high normal T4 concentration and
           Hyperpigmented areas (“freckles”) in orange (gin-
                                                          signs consistent with hyperthyroidism should either be
           ger) cats are termed lentigo simplex.
                                                          retested several weeks later, or free T4 concentration be
           Freckles usually appear  before 1 year of age and  measured by equilibrium dialysis, or a T3 suppression
           increase in number with age.                   test performed. Concurrent disease can decrease a high
                                                          T into the normal range.
           There are multiple hypermelanotic macular lesions on  4
           the nose, lips, eyelids and footpads.
                                                          FELINE POX VIRUS INFECTION**
           Lesions are  asymptomatic and do not develop into
           melanomas.
                                                           Classical signs
                                                           ● Multiple nodules, papules, crusts, and
                                                             ulcerative plaques.
           Diagnosis
                                                           ● Commonly on the face, limbs and paws.
           Diagnosis is based on the history of asymptomatic  ● Pruritis, pain, fever, conjunctivitis and
           black spots developing in the poorly haired areas of  dyspnea may be present.
           cats with a ginger coat color.
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