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1158  PART 14  QUEEN AND KITTEN WITH PROBLEMS


          Diagnosis                                     Prognosis

          Ovarian tumors may be large enough to be seen on plain  Prognosis is guarded for ovarian tumors in cats, as
          radiographs. They displace coils of the small intestine in  most are malignant, and they are the most common
          the cranial and mid-abdomen. Retrograde vaginography  type of tumor to metastasize.
          using a positive contrast agent may be used to demon-
                                                        Uterine tumors have a much better prognosis as the
          strate vaginal masses. At estrus the cervix will be open
                                                        most common types are benign.
          and allow the contrast agent into lumen of the uterus and
          this may demonstrate uterine neoplasia.
          Abdominal ultrasound and biopsy are invaluable to  Prevention
          diagnose the primary tumor and detect metastases
          to abdominal organs.                          Ovariohysterectomy at a young age eliminates the
                                                        chance of these tumors occurring. In a queen required
          As some tumors have been reported to metastasize to
                                                        for breeding this is not an option. However, she should
          the lungs, thoracic radiographs should be done prior
                                                        undergo ovariohysterectomy as soon as she is no longer
          to treatment.
                                                        required for breeding.
          ● Exploratory surgery and biopsy or tumor removal
            provide a definitive diagnosis, and are the best
            method of checking for metastases.          HYPOVITAMINOSIS A

          Differential diagnosis                         Classical signs
          Ovarian cysts can appear very similar to ovarian  ● Weight loss, anorexia, hyperkeratosis of
          tumors.                                          epithelial tissues, failure of glandular
          ● They occur frequently in older queens.         secretions, corneal infections, night
          ● Ultrasound may be able to differentiate these.  blindness and retinal atrophy.
            – Ovarian cysts have thin walls with anechoic con-  ● Lack of estrus cycles.
               tents. Acoustic enhancement is a feature.  ● Fetal resorption or abortion.
            – Ovarian neoplasia can be recognized as a mass  ● A high proportion of the kittens with
               lesion of varying size and echo-texture, maybe  defects.
               multicystic, but usually with irregular margins
               and irregular septae.                    Pathogenesis
          ● Surgical removal and histopathology give a defin-
            itive diagnosis.                            Inadequate vitamin A in the diet.  Cats require pre-
                                                        formed vitamin A in the diet as they are unable to
                                                        process carotene into vitamin A.
          Treatment
                                                         ● With the ready availability of good-quality commer-
          Surgical removal of the ovary(ies) affected by tumor.  cial diets, a deficiency should be a rare occurrence.
          ● A complete ovariohysterectomy is the treatment of  – There is a possibility of deficiency where a poor-
            choice as there may be uterine pathology associated  quality commercial diet or inadequate home-
            with hormonally active tumors. Only leave the uterus  prepared food is fed.
            if one ovary is unaffected and there is to be an attempt
            at gaining a litter from an important queen.  Clinical signs
          ● Chemotherapy treatment for these tumors has not
            been reported. Cisplatin has been used in human and  Failure of implantation may occur. This presents as a
            canine ovarian carcinomatosis, but this drug is con-  queen with normal mating but fails to produce kittens.
            traindicated in cats.
                                                        There is a high proportion of kittens with cleft palates,
          Ovariohysterectomy should be curative for benign  spina bifida, hydrocephaly and defects of the
          tumors.                                       diaphragm.
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