Page 1192 - Problem-Based Feline Medicine
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1184  PART 15  CAT WITH EYE PROBLEMS


          retinal detachment. Check these cats for renal disease  Diagnosis
          and hyper-thyroidism.
                                                        Old cats that have a prior history of trauma, and present
          Inflammatory chorioretinitis is always appears as  with glaucoma and signs of uveitis and keratitis, are
          cloudy eyes that have uveitis. Laboratory tests are use-  candidates for this rare condition.
          ful to confirm diagnoses.
                                                        Fine-needle biopsy may be done, but may not yield
          Treatment                                     a diagnostic sample if the tumor contains fibrous and
                                                        cartilagenous tissue.
          There is no treatment for this form of retinal degener-
                                                        Histopathology of enucleated globes provides a defin-
          ation. Breeders need to be made aware of the mode of
                                                        itive diagnosis, and will show changes that may include
          inheritance.
                                                        granulation tissue, fibrosarcoma, osteosarcoma and
          TRAUMA-ASSOCIATED OCULAR SARCOMA              anaplastic spindle cell sarcoma.

           Classical signs                              Treatment
           ● Rare, primary neoplasia that occurs in     All blind globes with chronic uveitis should be
             older cats (7–15 years).                   watched for the development of this condition.
           ● History of previous severe trauma to eye.
                                                        Early enucleation with histopathology should be
           ● Anterior uveitis, keratitis (corneal edema
                                                        done on all globes where there is a prior history of
             and pigmentation) and glaucoma.
                                                        trauma, and there are changes in the size and shape
           ● White to pinkish masses may be visible in
                                                        of the globe, or changes in the anterior chamber and
             the vitreous.
                                                        cornea, that are indicative of intra-ocular disease.
          Clinical signs                                Severely traumatized blind eyes in cats should be
                                                        enucleated, to prevent the occurrence of this condition,
          Trauma-associated ocular sarcoma is a rare primary  particularly if there has been lens rupture.
          neoplasia reported only in cats.
                                                        In confirmed cases, check for metastases to regional
          It occurs in older cats, typically  7–15 years of age  lymph nodes, and other organs such as lungs and liver.
          that have had a history of ocular trauma 3–10 years
          previously.
                                                        METASTATIC INTRA-RETINAL NEOPLASIA
          Signs of anterior uveitis and keratitis may be evident,
          as edema and pigmentation of the cornea, and a cloudy
                                                         Classical signs
          eye. These changes may prevent visualization of the
          intra-ocular structures.                       ● Rare in cats.
                                                         ● Uveitis with corneal edema, cloudy
          Secondary glaucoma is common at this stage of the
                                                           aqueous and distorted pupil.
          disease. The eye will show buphthalmos (enlarged globe)
                                                         ● Swelling and pigment changes in the
          with engorged scleral vessels.
                                                           retina.
          If the posterior segment can be visualized,  white to
          pink masses may be seen.
          The condition is thought to occur after lens trauma,  Clinical signs
          which triggers the  lens epithelial cells to undergo
                                                        This is a rare condition in cats.
          metaplasia.
                                                        Most cases present as  anterior uveitis with corneal
          The neoplasia rapidly extends through the choroid, and
                                                        edema and a cloudy aqueous, and have some form of
          infiltrates the optic nerve. Metastasis has been reported.
                                                        swelling seen in the iris, which may cause distortion of
          Survival rate is very low.                    the pupil (dyscoria).
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