Page 527 - Problem-Based Feline Medicine
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23 – THE BLEEDING CAT  519


           Diagnosis                                      CUTANEOUS ASTHENIA (EHLERS–DANLOS

           See The Cat With Depression, Anorexia or       SYNDROME)
           Dehydration (page 273).
                                                           Classical signs
           Hemostatic testing may reveal evidence of DIC (e.g.
           thrombocytopenia, prolongation of clotting times), evi-  ● Excessive wounding since birth.
           dence of  vitamin K deficiency (prolonged PT and  ● Subcutaneous hematomas or seromas.
           PIVKA time), and/or evidence of other hemostatic dis-
           orders associated with concurrent liver disease (see
           Liver disease, above).                         Clinical signs

                                                          Signs are present from birth, but may worsen with age.
           Differential diagnosis
                                                          Skin is hyperextensive and wounds easily with minor
           See The Cat With Depression, Anorexia or
                                                          trauma, and may feel softer. Scars from previous
           Dehydration (page 275). Pancreatitis is difficult to
                                                          wounds may be present. Signs result from abnormal
           definitively diagnose without biopsy. Many diseases in
                                                          collagen synthesis, and will vary in degree with the spe-
           the cat cause non-specific signs and sub-clinical hemo-
                                                          cific genetic defect.
           static defects. Systematic elimination of diseases by
                                                          ● The chief complaint may be  bleeding from the
           work-up helps narrow the list of differential diagnoses.
                                                             skin, but bleeding is appropriate for the wound.
                                                          ● Bleeding into the skin without a wound (petechia-
           Treatment                                         tion, ecchymoses) is not characteristic of the dis-
                                                             eases described to date in cats.
           See The Cat With Depression, Anorexia or
                                                          ● Subcutaneous hematomas and seromas may
           Dehydration (page 277).
                                                             occur because blood and lymphatic vessels are
           If there is clinical bleeding, treat with vitamin K as for  fragile or are injured when the skin stretches.
           liver diseases and transfusions as for DIC.
                                                          Concurrent signs include  joint laxity, lens luxation
                                                          and cataracts.
                                                          Reported in domestic shorthaired, domestic longhaired,
           STRANGULATION
                                                          Himalayan and Burmese cats.
            Classical signs
            ● Scleral hemorrhage.
                                                          Diagnosis
                                                          Clinical signs are highly suggestive.
           Clinical signs
                                                          Skin extensibility index (SEI) > 19%. SEI = height of
           Non-fatal strangulation may result in scleral edema and  fold/body length × 100, where, with the cat standing, a
           hemorrhage, and neurologic signs. Pulmonary edema  fold of lumbosacral skin is pulled upwards and the
           has also been seen in dogs.                    height from the top of the spine to the top of the fold is
                                                          measured, and body length is measured from the occipi-
                                                          tal crest to the base of the tail.
           Diagnosis
                                                          Skin biopsy for histopathology and/or electron
           History is diagnostic. Usually the collar or leash is
                                                          microscopy of skin to document collagen abnormali-
           caught in a tree.
                                                          ties, special biochemical analyses, and measurement of
           Skin lesions around neck.                      tensile strength.
           Hemostatic testing is normal.                  Hemostatic testing is normal.
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