Page 595 - Problem-Based Feline Medicine
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27 – THE CAT WITH SALIVATION  587


           Treat concurrent skin allergy and  ectoparasites to  Differential diagnosis
           achieve control.
                                                          Inflammatory polyps – usually have stalk.
           Change to a novel protein diet.
                                                          Intra-oral abscess and granulation tissue can have a
           Regular manual grooming and bathing.           similar appearance – differentiate by  biopsy or trial
                                                          antibiotics.
           Prednisolone (2 mg/kg PO q 12 h for 5–10 days, then
           taper).                                        Eosinophilic granuloma complex (linear granu-
                                                          loma) has characteristic white-yellow nodules – dif-
           Megestrol acetate (2.5–5 mg/cat PO for 4 days, then
                                                          ferentiate by biopsy or trial corticosteroids.
           2.5–5 mg q 5–7 days until lesions regress).
           NB This drug, although very effective, has numerous side
           effects especially in the Burmese breed (diabetes melli-  Treatment
           tus, pyometra, obesity, iatrogenic Cushings disease).
                                                          Treatment of lingual squamous cell carcinoma in the
           Cyclosporine (5 mg/kg PO q 12–24h).            cat has not proved successful, however some of the
                                                          newer chemotherapic agents may be more effective
           Doxycycline (2.5 mg/kg PO q 24h).
                                                          combined with tumor excision.
                                                          Mandibular masses can be treated by  partial
           ORAL NEOPLASIA *                               mandibulectomy.

            Classical signs
                                                          Prognosis
            ● Ptyalism, often blood stained.
                                                          Grave for squamous cell carcinoma of the tongue.
            ● Halitosis.
            ● Dysphagia.                                  For other tumors, the prognosis will depend on the
                                                          tumor type and suitability for treatment.
           Pathogenesis
           Squamous cell carcinoma is the most common neo-
                                                          HOUSEHOLD CLEANERS AND
           plasm. Usually on the ventral surface of the tongue
                                                          DISINFECTANTS*
           causing immobility of the tongue but sometimes tonsil-
           lar crypt or under the canine tooth.
                                                           Classical signs
           Usually in older cats (> 10 years).
                                                           ● Ptyalism, acute onset.
           Other tumors include epulis, fibroscarcoma and lym-  ● Dysphagia.
           phoscarcoma.                                    ● Depression, saliva-stained front feet.

           Clinical signs
           Excessive salivation, often blood stained. Signs usually  Pathogenesis
           present longer than 1 week.
                                                          Most common household cleaning products and disin-
           Dysphagia, difficulty in prehension.           fectants are extremely toxic to cats.
           Facial distortion, halitosis.                  These include chlorine (sodium hypochlorite), strong
                                                          alkalis, strong acids, pine oils, phenolic compounds,
           Weight loss due to inability to eat or metastatic disease.
                                                          hydrocarbons and  quaternary ammonium com-
                                                          pounds.
           Diagnosis
                                                          Most cause  contact necrosis of  skin and  mucous
           Biopsy and histologic examination.
                                                          membranes especially if undiluted or incorrectly
           Radiography to assess extent of tumor invasion.  diluted.
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