Page 636 - Problem-Based Feline Medicine
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628   PART 9   CAT WITH SIGNS OF GASTROINTESTINAL TRACT DISEASE


          Mydriasis is present with normal vision and third eye-  There are no other abnormal clinical findings other
          lids are commonly prolapsed.                  than the cat appears to gulp or swallow its food without
                                                        chewing it.
          Keratoconjunctivitis sicca and dry oral mucous
          membranes may be present.
                                                        Diagnosis
          Other signs include  bradycardia (60–120 bpm) and
          hypotension                                   All clinical, biochemical, radiographic and endo-
                                                        scopic studies (if performed) will be normal.
          Anal areflexia has been reported.
                                                        This is a diagnosis of clinical presumption based on
          Dysuria in association with a distended urinary
                                                        history, physical exam and the ability to control the
          bladder also occurs.
                                                        signs by feeding smaller meals more frequently or
          The disease is  rare in the US (some regional areas  reducing the competition for food that may create food
          especially in the central mid-west have more cases) but  gulping.
          was more common in Europe in the 1980s.

          It is usually seen in young (< 3 years) cats.  Differential diagnosis
                                                        Hiatal hernia, mild gastroesophageal reflux, mild
          Diagnosis
                                                        esophageal hypomotility or lower esophageal sphincter
          The constellation of clinical signs is suggestive of  disease.
          autonomic nervous system dysfunction.
                                                        Food intolerance and food allergy may cause vomiting
          There is  no definitive diagnostic test for dysauto-  very soon after eating which could be mistaken for
          nomia, but the following tests of autonomic function  regurgitation.
          are supportive:
          ● Intraocular  physostigmine fails to provoke a
                                                        Treatment
            response, but pilocarpine causes immediate miosis.
          ● Intradermal skin testing – There is no response to  Feed the cat smaller meals more frequently or change
            histamine (no wheal or flare).              feeding location or time to  reduce competition for
          ● Epinephrine should not be given to cats with  food or the tendency to eat rapidly.
            dysautonomia because fatal arrhythmias may
            develop.
                                                        MEDIASTINAL NEOPLASIA
          ● Cats will respond to atropine (increased heart rate),
            which proves that the post-ganglionic receptors are
                                                         Classical signs
            still able to appropriately respond to stimulus.
                                                         ● Anorexia.
                                                         ● Regurgitation.
          EATING TOO FAST (FOOD GULPING)
                                                         ● Other systemic signs if paraneoplastic
                                                           disease occurs.
           Classical signs
                                                         ● Thymic lymphoma/thymoma is a
           ● Intermittent regurgitation of food            mostly benign anterior mediastinal
             immediately after ingestion, often in         mass, usually found in older cats. Most
             tubular form.                                 affected cats are FeLV negative and the
                                                           tumor may be associated with para-
                                                           neoplastic syndromes, such as
          Clinical signs
                                                           myasthenia gravis, polymyositis,
          Intermittent regurgitation of whole food, often in  myocarditis or dermatitis.
          tubular form, immediately after it is consumed.
                                                        See main reference on page 56 for details.
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